MRP5 Blocking Peptide | ABCC5 blocking peptide

MRP5 Immunizing Peptide

Gene Names

ABCC5; MRP5; SMRP; ABC33; MOATC; MOAT-C; pABC11; EST277145

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow

Synonyms

MRP5; MRP5 Immunizing Peptide; DKFZp686C1782; ABCC5; ATP-binding cassette; sub-family C (CFTR/MRP); member 5; ABC33; EST277145; MOAT-C; MOATC; SMRP; pABC11; sub-family C; canalicular multispecific organic anion transporter C; ABCC5 blocking peptide

Ordering
Cat. Num. AAA426635 When autocomplete results are available use up and down arrows to review and enter to select. Touch device users, explore by touch or with swipe gestures. For Research Use Only!

Reactivity

Human, Mouse, Rat, Dog, Pig, Cow

Form/Format

100ug of dried peptide

Sequence

KDIDIGKEYIIP-C

Sequence Length

1437

Preparation and Storage

Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #

66529005

NCBI GeneID

10057

NCBI Accession #

NP_005679.2; NP_001018881.1

NCBI GenBank Nucleotide #

NM_005688.3

Molecular Weight

155,732 Da

NCBI Official Full Name

multidrug resistance-associated protein 5 isoform 1

NCBI Official Synonym Full Names

ATP binding cassette subfamily C member 5

NCBI Official Symbol

ABCC5

NCBI Official Synonym Symbols

MRP5; SMRP; ABC33; MOATC; MOAT-C; pABC11; EST277145

NCBI Protein Information

multidrug resistance-associated protein 5

UniProt Protein Name

Multidrug resistance-associated protein 5

Protein Family

Multidrug resistance-associated protein

UniProt Gene Name

ABCC5

UniProt Synonym Gene Names

MRP5; MOAT-C

UniProt Entry Name

MRP5_HUMAN

NCBI Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Description

ABCC5: Acts as a multispecific organic anion pump which can transport nucleotide analogs. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, ABC family; Transporter

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function: anion transmembrane-transporting ATPase activity; ATP binding; organic anion transmembrane transporter activity

Biological Process: hyaluronan biosynthetic process; organic anion transport; transmembrane transport; transport

Research Articles on ABCC5

1. ABCC5 is a general glutamate conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.

Similar Products

MRP5 Antibody

Host: Rabbit

Reactivity: Human, Mouse, Rat

Apps: ELISA, Immunohistochemistry

ABCC5 ELISA Kit

Host: n/a

Reactivity: Human

Apps: n/a

Product Notes

The ABCC5 abcc5 (Catalog #AAA426635) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The MRP5 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: KDIDIGKEYI IP-C. It is sometimes possible for the material contained within the vial of "MRP5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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