Tapasin Recombinant Protein | TAPBP recombinant protein

Tapasin Protein, Human, Recombinant (His Tag)

Cat. Num. AAA8121888

• Gene Names: TAPBP; TPN; TAPA; TPSN; NGS17
• Purity: >90% as determined by SDS-PAGE
• Synonyms: Tapasin; Tapasin Protein; Human; Recombinant (His Tag); Human TAPBP/ Tapasin Protein (His Tag); NGS17 Protein; TAPA Protein; TPN Protein; TPSN Protein; TAP binding protein (tapasin); TAPBP recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Val414

• Species: Human
• Endotoxin: <1.0EU per ug protein as determined by the LAL method.
• Predicted N Terminal: Gly 21
• Tag: C-His
• Protein Construction: A DNA sequence encoding the human TAPBP (AAH80574.1)(Met1-Val414) was expressed with a polyhistidine tag at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 51593768
• NCBI GeneID: 6892
• Molecular Weight: 38,365 Da
• NCBI Official Full Name: TAPBP protein
• NCBI Official Synonym Full Names: TAP binding protein
• NCBI Official Symbol: TAPBP
• NCBI Official Synonym Symbols: TPN; TAPA; TPSN; NGS17
• NCBI Protein Information: tapasin
• Protein Family: Tapasin

NCBI Description

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]