85 kDa calcium-independent phospholipase A2 (Pla2g6) Recombinant Protein | Pla2g6 recombinant protein

Recombinant Rat 85 kDa calcium-independent phospholipase A2 (Pla2g6), partial

• Gene Names: Pla2g6; iPla2; PNPLA9; GVI PLA2; caI-PLA2; iPLA2-beta
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: 85 kDa calcium-independent phospholipase A2 (Pla2g6); Recombinant Rat 85 kDa calcium-independent phospholipase A2 (Pla2g6); partial; Pla2g6 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 752

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Pla2g6 recombinant protein

This protein is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only two of them have been determined to date.

NCBI and Uniprot Product Information

• NCBI GI #: 53850648
• NCBI GeneID: 360426
• NCBI Accession #: NP_001005560.1
• NCBI GenBank Nucleotide #: NM_001005560.1
• UniProt Accession #: P97570; Q66HD1; G3V7M8
• Molecular Weight: 83,562 Da
• NCBI Official Full Name: 85/88 kDa calcium-independent phospholipase A2 isoform 1
• NCBI Official Synonym Full Names: phospholipase A2 group VI
• NCBI Official Symbol: Pla2g6
• NCBI Official Synonym Symbols: iPla2; PNPLA9; GVI PLA2; caI-PLA2; iPLA2-beta
• NCBI Protein Information: 85/88 kDa calcium-independent phospholipase A2
• UniProt Protein Name: 85/88 kDa calcium-independent phospholipase A2
• Protein Family: 85/88 kDa calcium-independent phospholipase
• UniProt Gene Name: Pla2g6
• UniProt Synonym Gene Names: Pnpla9; CaI-PLA2; GVI PLA2; iPLA2-beta; PNPLA9

NCBI Description

has Ca2+ independent phospholipase A2 activity; may play a role in regulating transmembrane ionic fluxes in pancreatic beta cells [RGD, Feb 2006]

Uniprot Description

Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods ().