Proheparin-binding EGF-like growth factor (Hbegf) Recombinant Protein | Hbegf recombinant protein
Recombinant Rat Proheparin-binding EGF-like growth factor (Hbegf)
Gene Names
Hbegf; Dtr; GFHB; Hegfl; Hb-egf
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Proheparin-binding EGF-like growth factor (Hbegf); Recombinant Rat Proheparin-binding EGF-like growth factor (Hbegf); Proheparin-binding EGF-like growth factorCleaved into the following chain:; 1. Heparin-binding EGF-like growth factor; 2. HB-EGF; 3. HBEGF; Hbegf recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
24-160
Sequence
ESLERLR RGLAAATSNP DPPTGTTNQL LPTGADRAQE VQDLEGTDLD LFKVAFSSKP QALATPGKEK NGKKKRKGKG LGKKRDPCLK KYKDYCIHGE CRYLKELRIP SCHCLPGYHG QRCHGLTLPV ENPLYTYDHT
Sequence Length
137
Species
Rattus norvegicus (Rat)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,843 Da
NCBI Official Full Name
proheparin-binding EGF-like growth factor
NCBI Official Synonym Full Names
heparin-binding EGF-like growth factor
NCBI Official Symbol
Hbegf
NCBI Official Synonym Symbols
Dtr; GFHB; Hegfl; Hb-egf
NCBI Protein Information
proheparin-binding EGF-like growth factor; heparin-binding epidermal -growth factor; heparin-binding epidermal -growth - like growth factor; heparin binding epidermal growth factor-like growth factor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor)
UniProt Protein Name
Proheparin-binding EGF-like growth factor
Protein Family
UniProt Gene Name
Hbegf
UniProt Synonym Gene Names
Dtr; Hegfl; HB-EGF; HBEGF
UniProt Entry Name
HBEGF_RAT
NCBI Description
activates epidermal growth factor receptor mediated signaling; contributes to neuronal survival; may play a role in neurogenesis during ventral midbrain development [RGD, Feb 2006]
Uniprot Description
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor ().
Research Articles on Hbegf
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Product Notes
The Hbegf hbegf (Catalog #AAA967319) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-160. The amino acid sequence is listed below: ESLERLR RGLAAATSNP DPPTGTTNQL LPTGADRAQE VQDLEGTDLD LFKVAFSSKP QALATPGKEK NGKKKRKGKG LGKKRDPCLK KYKDYCIHGE CRYLKELRIP SCHCLPGYHG QRCHGLTLPV ENPLYTYDHT. It is sometimes possible for the material contained within the vial of "Proheparin-binding EGF-like growth factor (Hbegf), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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