Rat Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) ELISA Kit | HBEGF elisa kit

Rat Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) ELISA Kit

Cat. Num. AAA451108

• Gene Names: Hbegf; Dtr; GFHB; Hegfl; Hb-egf
• Reactivity: Rat
• Synonyms: Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF); Rat Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF) ELISA Kit; HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor; HBEGF elisa kit

• Reactivity: Rat
• Sequence Length: 208

• Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 15.625-1000pg/mL
• Sensitivity: 6.2pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 6978785
• NCBI GeneID: 25433
• NCBI Accession #: NP_037077.1
• NCBI GenBank Nucleotide #: NM_012945.1
• UniProt Accession #: Q06175
• Molecular Weight: 22,843 Da
• NCBI Official Full Name: proheparin-binding EGF-like growth factor
• NCBI Official Synonym Full Names: heparin-binding EGF-like growth factor
• NCBI Official Symbol: Hbegf
• NCBI Official Synonym Symbols: Dtr; GFHB; Hegfl; Hb-egf
• NCBI Protein Information: proheparin-binding EGF-like growth factor
• UniProt Protein Name: Proheparin-binding EGF-like growth factor
• Protein Family: Proheparin-binding EGF-like growth factor
• UniProt Gene Name: Hbegf
• UniProt Synonym Gene Names: Dtr; Hegfl; HB-EGF; HBEGF

NCBI Description

activates epidermal growth factor receptor mediated signaling; contributes to neuronal survival; may play a role in neurogenesis during ventral midbrain development [RGD, Feb 2006]

Uniprot Description

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor ().