SH3 domain-binding protein 2 (SH3BP2) Recombinant Protein | SH3BP2 recombinant protein

Recombinant Human SH3 domain-binding protein 2 (SH3BP2)

Cat. Num. AAA966727

• Gene Names: SH3BP2; 3BP2; CRBM; CRPM; 3BP-2; RES4-23
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: SH3 domain-binding protein 2 (SH3BP2); Recombinant Human SH3 domain-binding protein 2 (SH3BP2); SH3BP2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-561, Full length protein
• Sequence: MAAEEMHWPVPMKAIGAQNLLTMPGGVAKAGYLHKKGGTQLQLLKWPLRFVIIHKRCVYYFKSSTSASPQGAFSLSGYNRVMRAAEETTSNNVFPFKIIHISKKHRTWFFSASSEEERKSWMALLRREIGHFHEKKDLPLDTSDSSSDTDSFYGAVERPVDISLSPYPTDNEDYEHDDEDDSYLEPDSPEPGRLEDALMHPPAYPPPPVPTPRKPAFSDMPRAHSFTSKGPGPLLPPPPPKHGLPDVGLAAEDSKRDPLCPRRAEPCPRVPATPRRMSDPPLSTMPTAPGLRKPPCFRESASPSPEPWTPGHGACSTSSAAIMATATSRNCDKLKSFHLSPRGPPTSEPPPVPANKPKFLKIAEEDPPREAAMPGLFVPPVAPRPPALKLPVPEAMARPAVLPRPEKPQLPHLQRSPPDGQSFRSFSFEKPRQPSQADTGGDDSDEDYEKVPLPNSVFVNTTESCEVERLFKATSPRGEPQDGLYCIRNSSTKSGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLLLRHPYGYTGPR
• Sequence Length: 561

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for SH3BP2 recombinant protein

This protein has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 170014705
• NCBI GeneID: 6452
• NCBI Accession #: NP_001116153.1
• NCBI GenBank Nucleotide #: NM_001122681.1
• UniProt Accession #: P78314; O00500; O15373; P78315; A6NNC2; B2R5R6; B4DT04; D3DVR0; D6R919
• Molecular Weight: 68,129 Da
• NCBI Official Full Name: SH3 domain-binding protein 2 isoform a
• NCBI Official Synonym Full Names: SH3 domain binding protein 2
• NCBI Official Symbol: SH3BP2
• NCBI Official Synonym Symbols: 3BP2; CRBM; CRPM; 3BP-2; RES4-23
• NCBI Protein Information: SH3 domain-binding protein 2
• UniProt Protein Name: SH3 domain-binding protein 2
• Protein Family: SH3 domain-binding protein
• UniProt Gene Name: SH3BP2
• UniProt Synonym Gene Names: 3BP2; 3BP-2

NCBI Description

The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Uniprot Description

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.