Amiloride-sensitive amine oxidase [copper-containing] (ABP1) Recombinant Protein | ABP1 recombinant protein

Recombinant Human Amiloride-sensitive amine oxidase [copper-containing] (ABP1)

Cat. Num. AAA966685

• Gene Names: AOC1; ABP; DAO; KAO; ABP1; DAO1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Amiloride-sensitive amine oxidase [copper-containing] (ABP1); Recombinant Human Amiloride-sensitive amine oxidase [copper-containing] (ABP1); ABP1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 20-751, Full length protein
• Sequence: EPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
• Sequence Length: 732

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for ABP1 recombinant protein

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and
or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and
or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

NCBI and Uniprot Product Information

• NCBI GI #: 73486661
• NCBI GeneID: 26
• NCBI Accession #: NP_001082.2
• NCBI GenBank Nucleotide #: NM_001091.3
• UniProt Accession #: P19801; Q16683; Q16684; Q56II4; Q6GU42; C9J690
• Molecular Weight: 87,239 Da
• NCBI Official Full Name: amiloride-sensitive amine oxidase
• NCBI Official Synonym Full Names: amine oxidase, copper containing 1
• NCBI Official Symbol: AOC1
• NCBI Official Synonym Symbols: ABP; DAO; KAO; ABP1; DAO1
• NCBI Protein Information: amiloride-sensitive amine oxidase [copper-containing]
• UniProt Protein Name: Amiloride-sensitive amine oxidase [copper-containing]
• Protein Family: ARS-binding protein
• UniProt Gene Name: AOC1
• UniProt Synonym Gene Names: ABP1; DAO1; DAO; Diamine oxidase; KAO

NCBI Description

This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]

Uniprot Description

Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.MiscellaneousInhibited by amiloride in a competitive manner.