ZP3 blocking peptide
ZP3 Antibody
NCBI and Uniprot Product Information
Uniprot Description
ZP3: The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. Belongs to the ZP domain family. ZPC subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Extracellular matrix
Chromosomal Location of Human Ortholog: 7q11.23
Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum; integral to membrane; acrosome; extracellular region; secretory granule; multivesicular body; extracellular matrix; proteinaceous extracellular matrix; perinuclear region of cytoplasm; cytoplasm; plasma membrane
Molecular Function: acrosin binding; signal transducer activity; protein binding; store-operated calcium channel activity; manganese ion transmembrane transporter activity; carbohydrate binding
Biological Process: positive regulation of type IV hypersensitivity; phosphoinositide-mediated signaling; binding of sperm to zona pellucida; positive regulation of transcription, DNA-dependent; positive regulation of leukocyte migration; manganese ion transport; blastocyst formation; positive regulation of phosphatidylinositol biosynthetic process; multicellular organism reproduction; positive regulation of interleukin-4 production; positive regulation of protein kinase B signaling cascade; humoral immune response mediated by circulating immunoglobulin; intracellular protein transport; positive regulation of interferon-gamma production; positive regulation of humoral immune response; positive regulation of protein kinase activity; single fertilization; positive regulation of T cell proliferation; negative regulation of transcription, DNA-dependent; oocyte development; positive regulation of inflammatory response
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Product Notes
The ZP3 zp3 (Catalog #AAA9633297) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ZP3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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