Rabbit anti-Human, Mouse INTS7 Polyclonal Antibody | anti-INTS7 antibody
INTS7 Antibody
Gene Names
INTS7; INT7; C1orf73; DKFZp434B168
Reactivity
Human, Mouse
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
INTS7; Polyclonal Antibody; INTS7 Antibody; 5930412E23Rik; C1orf73; Chromosome 1 open reading frame 73; chunp6916; DKFZp434B168; FLJ10736; FLJ12447; Int7; INT7_HUMAN; Integrator complex subunit 7; Ints7; Ints7 integrator complex subunit 7; OTTHUMP00000035211; RGD1308014; anti-INTS7 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
INTS7 Antibody detects endogenous levels of INTS7.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-INTS7 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human INTS7.
Conjugation
Unconjugated
Similarity
Belongs to the Integrator subunit 7 family.
Subunit Structure
Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12. Interacts with NABP2.
Function
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Plays a role in DNA damage response (DDR) signaling during the S phase. May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.
Note
Localizes to sites of DNA damage in a H2AX-independent manner.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-INTS7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
106,834 Da
NCBI Official Full Name
integrator complex subunit 7 isoform 1
NCBI Official Synonym Full Names
integrator complex subunit 7
NCBI Official Symbol
INTS7
NCBI Official Synonym Symbols
INT7; C1orf73; DKFZp434B168
NCBI Protein Information
integrator complex subunit 7; OTTHUMP00000035211; OTTHUMP00000035212; OTTHUMP00000035213
UniProt Protein Name
Integrator complex subunit 7
Protein Family
UniProt Gene Name
INTS7
UniProt Synonym Gene Names
C1orf73
UniProt Entry Name
INT7_HUMAN
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Product Notes
The INTS7 ints7 (Catalog #AAA9630842) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The INTS7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's INTS7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the INTS7 ints7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INTS7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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