The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
AHCYL2; Polyclonal Antibody; AHCYL2 Antibody; Adenosylhomocysteinase 3; Adenosylhomocysteinase3; AdoHcyase 3; AdoHcyase; AdoHcyase3; AHC; Ahcyl2; FLJ21719; Hypothetical protein FLJ27233; KIAA0828; Putative adenosylhomocysteinase 3; S adenosyl L homocysteine hydrolase 3; S adenosyl L homycysteine hydrolase; S-adenosyl-L-homocysteine hydrolase 3; S-adenosylhomocysteine hydrolase-like protein 2; SAH 3; SAHH3_HUMAN; anti-AHCYL2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
AHCYL2 Antibody detects endogenous levels of AHCYL2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-AHCYL2 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human AHCYL2.
Conjugation
Unconjugated
Similarity
Belongs to the adenosylhomocysteinase family.
Post Translational Modifications
Phosphorylated during neuronal differentiation at the LISN domain.
Subunit Structure
Homotetramer (Probable). Forms heteromultimers with AHCYL1 (via the C-terminal region). Interacts with ITPR1; with lower affinity than AHCYL1 and maybe via ITPR1. Interacts with SLC4A4 (By similarity).
Function
May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1, 4, 5-trisphosphate.
Note
Associates with membranes when phosphorylated, probably through interaction with ITPR1.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-AHCYL2 antibody
The AHCYL2 ahcyl2 (Catalog #AAA9630141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AHCYL2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AHCYL2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the AHCYL2 ahcyl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
It is sometimes possible for the material contained within the vial of
"AHCYL2, Polyclonal Antibody" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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