Complement component C9 (C9) Recombinant Protein | C9 recombinant protein
Recombinant Horse Complement component C9 (C9)
NCBI and Uniprot Product Information
Uniprot Description
Function: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC.
Subunit structure: Component of the membrane attack complex (MAC). MAC assembly is initiated by protelytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and multiple copies of the pore-forming subunit C9
By similarity.
Subcellular location: Secreted
By similarity. Cell membrane; Multi-pass membrane protein
By similarity. Note: Secreted as soluble monomer. Oligomerizes at target membranes, forming a pre-pore. A conformation change then leads to the formation of a 100 Angstrom diameter pore
By similarity.
Post-translational modification: Thrombin cleaves factor C9 to produce C9a and C9b.
Sequence similarities: Belongs to the complement C6/C7/C8/C9 family.Contains 1 EGF-like domain.Contains 1 LDL-receptor class A domain.Contains 1 MACPF domain.Contains 1 TSP type-1 domain.
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Product Notes
The C9 c9 (Catalog #AAA961232) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 22-547. The amino acid sequence is listed below: GPTPNYAPEP EQQSGTPLPI DCRMSSWSEW SECDPCLRQM FRSRSIEVFG QFNGQRCVDA VGDRRQCVPT EACEEVEDDC GNDFQCGTGR CIKKRLLCNG DNDCGDFSDE DDCENDPRPP CRERVVEESE LARTAGYGIN ILGMDPLSTP FDNEYYNGLC DRVRDGNTLT YYRKPWNLAS LAYETKADKN FRIEHYEQQI QAFRSVIEER RSHFNADFTL KFTPTEAKKC KQEPEESCNG TDSSENRIFR FAYSKNETYQ LFLSYSSKKE KMFLHVKGVI QLGKFVMRSR DVVLTTTFLD DIKALPTAYE KGEYIAFLET YGTHYSSSGS LGGLYELIYV LDKASMDQKG VELRDIQRCL GFNLDLSLKD KYEVTAKIDK NDCLKRNEKE IVNIMDGSLI DDVISLIRGG TRKYAFELKE KLLKGAKTVN VTDFVNWASS LNDAPVLISQ RLSPIYNLIP VKMKDAHQKK QNLERAIEDY INEFSVRKCH PCQNGGTVIQ IDGQCLCSCP IAFEGIACET GKKKIS. It is sometimes possible for the material contained within the vial of "Complement component C9 (C9), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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