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Western Blot (WB) (Western blot analysis of PCDH-X/Y using HeLa whole cell lysates)

Rabbit anti-Human PCDH-X/Y Polyclonal Antibody | anti-PCDH11Y antibody

PCDH-X/Y Antibody

Gene Names
PCDH11Y; PCDHX; PCDHY; PCDH22; PCDH-PC
Reactivity
Human
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PCDH-X/Y; Polyclonal Antibody; PCDH-X/Y Antibody; PCDH 11; PCDH 11X; PCDH 11Y; PCDH 22; PCDH PC; PCDH Y; PCDH11; PCDH11X; PCDH22; PCDHY; Protocadherin 11; Protocadherin 11 X linked; Protocadherin 11 Y linked; Protocadherin 22; Protocadherin on the Y chromosome; Protocadherin PC; Protocadherin prostate cancer; Protocadherin Y; Protocadherin11; Protocadherin22; ProtocadherinY; PC11X_HUMAN; PCDH-X; PCDHX; PPP1R119; Protein phosphatase 1 regulatory subunit 119; Protocadherin 11X; Protocadherin on the X chromosome; Protocadherin-11; Protocadherin-11 X-linked; Protocadherin-S; anti-PCDH11Y antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
PCDH-X/Y antibody detects endogenous levels of total PCDH-X/Y
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
1037
Applicable Applications for anti-PCDH11Y antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PCDH-X/Y
Subcellular Location
Cell Membrane; Single-Pass Type I Membrane Protein
Tissue Specificity
Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Expressed in apoptosis-resistant cells.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of PCDH-X/Y using HeLa whole cell lysates)

Western Blot (WB) (Western blot analysis of PCDH-X/Y using HeLa whole cell lysates)
Related Product Information for anti-PCDH11Y antibody
Function: Potential calcium-dependent cell-adhesion protein.
Subunit Structure: Interacts with CTNNB1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 146 kDa
Predicted: 147 kDa
NCBI Official Full Name
protocadherin-11 Y-linked isoform a
NCBI Official Synonym Full Names
protocadherin 11 Y-linked
NCBI Official Symbol
PCDH11Y
NCBI Official Synonym Symbols
PCDHX; PCDHY; PCDH22; PCDH-PC
NCBI Protein Information
protocadherin-11 Y-linked
UniProt Protein Name
Protocadherin-11 Y-linked
Protein Family
UniProt Gene Name
PCDH11Y
UniProt Synonym Gene Names
PCDH11; PCDH22; PCDHY; Protocadherin-11; PCDH-Y; Protocadherin-PC

NCBI Description

This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Uniprot Description

Potential calcium-dependent cell-adhesion protein.

Research Articles on PCDH11Y

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Product Notes

The PCDH11Y pcdh11y (Catalog #AAA9609184) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCDH-X/Y Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCDH-X/Y can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PCDH11Y pcdh11y for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCDH-X/Y, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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