Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7602429 (PCDH11Y antibody) at dilution of 1:300)
Rabbit anti-Human PCDH11Y Polyclonal Antibody | anti-PCDH11Y antibody
PCDH11Y Rabbit Polyclonal
Immunogen Affinity Purified
Immunogen Affinity Purified
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7602429 (PCDH11Y antibody) at dilution of 1:300)
Western Blot (WB)
(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS7602429 (PCDH11Y antibody) at dilution of 1:300)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
PCDH11Y: Potential calcium-dependent cell-adhesion protein. A chromosomal aberration involving PCDH11Y is a cause of multiple congenital abnormalities, including severe bilateral vesicoureteral reflux (VUR) with ureterovesical junction defects. Translocation t(Y;3)(p11;p12) with ROBO2. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: Yp11.2
Cellular Component: integral to membrane; plasma membrane
Molecular Function: calcium ion binding
Biological Process: homophilic cell adhesion
Research Articles on PCDH11Y
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Product Notes
The PCDH11Y pcdh11y (Catalog #AAA7602429) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCDH11Y Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCDH11Y can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the PCDH11Y pcdh11y for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCDH11Y, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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