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Western Blot (WB) (Western blot analysis of ARMCX1 using HeLa whole cell lysates)

Rabbit anti-Human, Rat ARMCX1 Polyclonal Antibody | anti-ARMCX1 antibody

ARMCX1 Antibody

Gene Names
ARMCX1; ALEX1; GASP7
Reactivity
Human, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
ARMCX1; Polyclonal Antibody; ARMCX1 Antibody; ARMCX 1; AD032; ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; Arm protein lost in epithelial cancers X chromosome 1; Armadillo repeat containing X linked 1; Armadillo repeat containing X linked protein 1; Armadillo repeat-containing X-linked protein 1; ARMX1_HUMAN; Protein ALEX1; anti-ARMCX1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
ARMCX1 antibody detects endogenous levels of total ARMCX1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
453
Applicable Applications for anti-ARMCX1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000
Immunogen
A synthesized peptide derived from human ARMCX1
Subcellular Location
Membrane.
Tissue Specificity
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
Predicted Cross Reactivity
Pig, Sheep, Dog
Similarity
Pig (82%), Sheep (82%), Dog (83%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of ARMCX1 using HeLa whole cell lysates)

Western Blot (WB) (Western blot analysis of ARMCX1 using HeLa whole cell lysates)
Related Product Information for anti-ARMCX1 antibody
Function: Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
Subunit Structure: Interacts with MIRO1.
Similarity: Belongs to the eutherian X-chromosome-specific Armcx family.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 49 kDa
Predicted: 50 kDa
NCBI Official Full Name
armadillo repeat-containing X-linked protein 1
NCBI Official Synonym Full Names
armadillo repeat containing X-linked 1
NCBI Official Symbol
ARMCX1
NCBI Official Synonym Symbols
ALEX1; GASP7
NCBI Protein Information
armadillo repeat-containing X-linked protein 1
UniProt Protein Name
Armadillo repeat-containing X-linked protein 1
UniProt Gene Name
ARMCX1
UniProt Synonym Gene Names
ALEX1; Protein ALEX1

NCBI Description

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008]

Uniprot Description

Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.

Research Articles on ARMCX1

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Product Notes

The ARMCX1 armcx1 (Catalog #AAA9602057) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ARMCX1 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARMCX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000. Researchers should empirically determine the suitability of the ARMCX1 armcx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARMCX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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