Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2) Recombinant Protein | ITIH2 recombinant protein
Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2)
Gene Names
ITIH2; H2P; SHAP
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2); Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2); ITIH2 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
55-702aa; Full Length of Mature Protein
Sequence
SLPGESEEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVEND
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
106,463 Da
NCBI Official Full Name
inter-alpha-trypsin inhibitor heavy chain H2
NCBI Official Synonym Full Names
inter-alpha-trypsin inhibitor heavy chain 2
NCBI Official Symbol
ITIH2
NCBI Official Synonym Symbols
H2P; SHAP
NCBI Protein Information
inter-alpha-trypsin inhibitor heavy chain H2
UniProt Protein Name
Inter-alpha-trypsin inhibitor heavy chain H2
Protein Family
UniProt Gene Name
ITIH2
UniProt Synonym Gene Names
IGHEP2; ITI heavy chain H2; ITI-HC2; Inter-alpha-inhibitor heavy chain 2; SHAP
NCBI Description
The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]).[supplied by OMIM, Nov 2009]
Uniprot Description
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Research Articles on ITIH2
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Product Notes
The ITIH2 itih2 (Catalog #AAA957308) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 55-702aa; Full Length of Mature Protein. The amino acid sequence is listed below: SLPGESEEMM EEVDQVTLYS YKVQSTITSR MATTMIQSKV VNNSPQPQNV VFDVQIPKGA FISNFSMTVD GKTFRSSIKE KTVGRALYAQ ARAKGKTAGL VRSSALDMEN FRTEVNVLPG AKVQFELHYQ EVKWRKLGSY EHRIYLQPGR LAKHLEVDVW VIEPQGLRFL HVPDTFEGHF DGVPVISKGQ QKAHVSFKPT VAQQRICPNC RETAVDGELV VLYDVKREEK AGELEVFNGY FVHFFAPDNL DPIPKNILFV IDVSGSMWGV KMKQTVEAMK TILDDLRAED HFSVIDFNQN IRTWRNDLIS ATKTQVADAK RYIEKIQPSG GTNINEALLR AIFILNEANN LGLLDPNSVS LIILVSDGDP TVGELKLSKI QKNVKENIQD NISLFSLGMG FDVDYDFLKR LSNENHGIAQ RIYGNQDTSS QLKKFYNQVS TPLLRNVQFN YPHTSVTDVT QNNFHNYFGG SEIVVAGKFD PAKLDQIESV ITATSANTQL VLETLAQMDD LQDFLSKDKH ADPDFTRKLW AYLTINQLLA ERSLAPTAAA KRRITRSILQ MSLDHHIVTP LTSLVIENEA GDERMLADAP PQDPSCCSGA LYYGSKVVPD STPSWANPSP TPVISMLAQG SQVLESTPPP HVMRVEND . It is sometimes possible for the material contained within the vial of "Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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