Rabbit TESK1 Polyclonal Antibody | anti-TESK1 antibody

TESK1 Antibody

Cat. Num. AAA9506306

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Synonyms: TESK1; Polyclonal Antibody; TESK1 Antibody; anti-TESK1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: TESK1 Antibody detects endogenous levels of total TESK1 protein.
• Purity/Purification: Purified from rabbit antiserum by affinity-chromatography using immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 626

• Applicable Applications for anti-TESK1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500~1:1000; ELISA: 1:40000
• Target Modification: Unmodified/Total
• Immunogen: The antiserum was produced against synthesized peptide derived from human TESK1.
• Immunogen Range: 181-230
• Preparation and Storage: Stable at -20 degree C for at least 1 year.

Western Blot (WB)

(Western blot analysis of lysates from rat heart, rat kidney, and rat liver cells, using TESK1 Antibody. The lane on the right is blocked with the synthesized peptide.)

NCBI and Uniprot Product Information

• NCBI GI #: 970841896
• NCBI GeneID: 7016
• NCBI Accession #: NP_001305159.1
• NCBI GenBank Nucleotide #: NM_001318230.1
• UniProt Accession #: Q15569; Q8IXZ8
• Molecular Weight: 67 kDa
• NCBI Official Full Name: dual specificity testis-specific protein kinase 1 isoform 2
• NCBI Official Synonym Full Names: testis-specific kinase 1
• NCBI Official Symbol: TESK1
• NCBI Protein Information: dual specificity testis-specific protein kinase 1
• UniProt Protein Name: Dual specificity testis-specific protein kinase 1
• Protein Family: Dual specificity testis-specific protein kinase
• UniProt Gene Name: TESK1

NCBI Description

This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Uniprot Description

Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis ().