NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Uniprot Description
RFX2: a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; DNA binding transcription factor activity; protein binding
Biological Process: acrosome formation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; spermatid development; transcription, DNA-dependent
Research Articles on RFX2
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Product Notes
The Human, Mouse, Rat RFX2 rfx2 (Catalog #AAA9502241) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9502241 ELISA Kit recognizes Human, Mouse, Rat RFX2. It is sometimes possible for the material contained within the vial of "RFX2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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