Rabbit anti-Mouse, Rat Uteroglobin Polyclonal Antibody | anti-Scgb1a1 antibody
Uteroglobin Antibody FITC Conjugated
Gene Names
Scgb1a1; UG; UGB; Utg; CC10; CC16; CCSP; PCB-BP
Reactivity
Mouse, Rat
Applications
Immunofluorescence
Purity
Purified by Protein A
Synonyms
Uteroglobin; Polyclonal Antibody; Uteroglobin Antibody FITC Conjugated; secretoglobin; family 1A; member 1; Scgb1a1; CC10; CC16; CCSP; PCB-BP; UG; UGB; Utg Uteroglobin; anti-Scgb1a1 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-Scgb1a1 antibody
Immunofluorescence (IF)
Application Notes
IF: 1:50-200
Conjugation
FITC
Excitation Emission
494nm 518nm
Immunogen
KLH conjugated synthetic peptide derived from mouse Uteroglobin
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-Scgb1a1 antibody
Uteroglobin belongs to the family of secretoglobins and is a secreted protein product of nonciliated bronchiolar Clara cells. There is convincing data suggesting it has phospholipase A2 inhibitory activity, as well as, a number of other immunomodulatory features including inhibition of interferon gamma signalling and Th1 vs. Th2 lymphocyte regulation. It was proposed as a potential peripheral marker of respiratory epithelial injury and bronchial dysfunction. Clara Cell Protein 16 concentrations have been determined in both serum and bronchoalveolar lavage fluid in numerous studies since 1994. In serum, its increase is associated with age, asbestos, nitrogen chloride and ozone exposure, sarcoidosis and high PEEP ventilation. Decreased serum CC16 levels are found after pulmonary resection, in silica-exposed workers, smokers and in asthma. Decreased CC16 concentrations were also found in the amniotic fluid of fetuses suffering from pulmonary hypoplasia caused by various mechanisms (diaphragmatic hernia, diabetic fetopathy, Turner and Down syndrome). In pleural effusions, the CC16 concentration appears to be associated with its diffusion from the lung as evidenced by high CC16 levels in cardiac pleural congestion.
Product Categories/Family for anti-Scgb1a1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,519 Da
NCBI Official Full Name
uteroglobin
NCBI Official Synonym Full Names
secretoglobin, family 1A, member 1 (uteroglobin)
NCBI Official Symbol
Scgb1a1
NCBI Official Synonym Symbols
UG; UGB; Utg; CC10; CC16; CCSP; PCB-BP
NCBI Protein Information
uteroglobin; Blastokinin; CCPBP; PCB-binding protein; clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; secretoglobin family 1A member 1
UniProt Protein Name
Uteroglobin
Protein Family
UniProt Gene Name
Scgb1a1
UniProt Synonym Gene Names
Cc10; Ugb; Utg; CCPBP; CC10
UniProt Entry Name
UTER_MOUSE
Uniprot Description
SCGB1A1: Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2. Belongs to the secretoglobin family.
Protein type: Secreted, signal peptide; Secreted; Inhibitor; Cell cycle regulation
Cellular Component: extracellular space; rough endoplasmic reticulum; endoplasmic reticulum; cytoplasm; extracellular region; nuclear envelope; intracellular; secretory granule
Molecular Function: phospholipase A2 inhibitor activity
Biological Process: negative regulation of interleukin-4 production; negative regulation of interleukin-13 production; negative regulation of T cell proliferation; response to cytokine stimulus; negative regulation of interferon-gamma production; regulation of inflammatory response; negative regulation of interleukin-5 production; negative regulation of transcription from RNA polymerase II promoter; regulation of mRNA stability; signal transduction
Research Articles on Scgb1a1
1. Suggest role for Scgb1a1(+) cells in the generation of p63(+) cells in the damaged lung parenchyma.
Similar Products
Product Notes
The Scgb1a1 scgb1a1 (Catalog #AAA9460850) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Uteroglobin Antibody FITC Conjugated reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Uteroglobin can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:50-200. Researchers should empirically determine the suitability of the Scgb1a1 scgb1a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Uteroglobin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
