Rabbit MC-1R MC1 Receptor Polyclonal Antibody | anti-MC-1R antibody
MC-1R MC1 Receptor Polyclonal Antibody Cy3 Conjugated
IF: 1:50-200
NCBI and Uniprot Product Information
Uniprot Description
MC1R: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Genetic variations in MC1R are a cause of susceptibility to cutaneous malignant melanoma type 5 (CMM5). Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral
Cellular Component: membrane; plasma membrane; integral to membrane; intracellular
Molecular Function: G-protein coupled receptor activity; protein binding; signal transducer activity; hormone binding; melanocortin receptor activity; melanocyte stimulating hormone receptor activity; ubiquitin protein ligase binding
Biological Process: melanin biosynthetic process; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; pigmentation; positive regulation of cAMP biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; negative regulation of tumor necrosis factor production; sensory perception of pain; signal transduction
Research Articles on MC-1R
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Product Notes
The MC-1R mc1r (Catalog #AAA9460651) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MC-1R MC1 Receptor Polyclonal Antibody Cy3 Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MC-1R MC1 Receptor can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Flow Cytometry (FC/FACS). FC/FACS:1:20-10 IF: 1:50-200. Researchers should empirically determine the suitability of the MC-1R mc1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MC-1R MC1 Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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