Rabbit anti-Fruit fly Cofilin Polyclonal Antibody | anti-Cofilin antibody
Cofilin Antibody
NCBI and Uniprot Product Information
Uniprot Description
Exhibits F-actin depolymerizing activity and regulates actin cytoskeleton dynamics (PubMed:21205790). Required for cytokinesis in both mitotic and meiotic cells and for aster migration and separation (PubMed:8522587). Promotes cell motility during ovary development and oogenesis (PubMed:11175754). During larval development, required for the cell rearrangement needed for formation of terminal filaments which are stacks of somatic cells that are important for the initiation of ovarioles (PubMed:11175754). Also required for border cell migration during oogenesis (PubMed:11175754). During border cell migration, required for actin turnover and lamellipodial protrusion (PubMed:21205790). Required for the establishment of planar cell polarity (PCP) where cells adopt a uniform orientation within the plane of an epithelium (PubMed:16571634). During establishment of PCP, required for the redistribution of the PCP core proteins fz and stan/fmi to the proximodistal cell boundary (PubMed:16571634). During pupal development, required for elongation of the retinal cell body and for rhabdomere morphogenesis (PubMed:18423434). Required for mushroom body neuroblast proliferation and axon growth (PubMed:15572110). Plays a role in the positive regulation of protein secretion (PubMed:20026655). Plays a role in the regulation of nuclear localization of actin (PubMed:22323606). Required for the maintenance of epithelial integrity by controlling cell junctions and is also necessary for cell survival and tissue growth through regulation of JNK and yki signaling (PubMed:27041568).
Research Articles on Cofilin
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Product Notes
The Cofilin tsr (Catalog #AAA9458474) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Cofilin Antibody reacts with Fruit fly and may cross-react with other species as described in the data sheet. AAA Biotech's Cofilin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the Cofilin tsr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cofilin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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