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Rabbit anti-Human FRS2 Polyclonal Antibody | anti-FRS2 antibody

FRS2 (Phospho-Tyr436) Polyclonal Conjugated Antibody

Gene Names
FRS2; SNT; SNT1; FRS2A; SNT-1; FRS2alpha
Reactivity
Human
Applications
Most Applications
Synonyms
FRS2; Polyclonal Antibody; FRS2 (Phospho-Tyr436) Polyclonal Conjugated Antibody; FRS2 (Phospho-Tyr436) Conjugated Antibody; SNT-1; SNT2; FGFR signalling adaptor; anti-FRS2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of FRS2 only when phosphorylated at tyrosine 436.
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-FRS2 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
Peptide sequence around phosphorylation site of tyrosine 436 (L-N-Y (p)-I-Q) derived from Human FRS2.
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.
Related Product Information for anti-FRS2 antibody
FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
57,029 Da
NCBI Official Full Name
fibroblast growth factor receptor substrate 2
NCBI Official Synonym Full Names
fibroblast growth factor receptor substrate 2
NCBI Official Symbol
FRS2
NCBI Official Synonym Symbols
SNT; SNT1; FRS2A; SNT-1; FRS2alpha
NCBI Protein Information
fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR signalling adaptor; FGFR-signaling adaptor SNT; suc1-associated neurotrophic factor target 1
UniProt Protein Name
Fibroblast growth factor receptor substrate 2
UniProt Gene Name
FRS2
UniProt Synonym Gene Names
FGFR substrate 2; SNT-1
UniProt Entry Name
FRS2_HUMAN

Uniprot Description

FRS2: an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: membrane; integral to plasma membrane; plasma membrane; intercellular junction; endosome

Molecular Function: protein binding; phosphatase activator activity; neurotrophin TRKA receptor binding; transmembrane receptor protein tyrosine kinase adaptor protein activity; insulin receptor binding; fibroblast growth factor receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; activation of MAPKK activity; activation of MAPK activity; gastrulation with mouth forming second; regulation of epithelial cell proliferation; regulation of apoptosis; G-protein coupled receptor protein signaling pathway; determination of anterior/posterior axis, embryo; induction of an organ; neuroblast proliferation; forebrain development; insulin receptor signaling pathway; innate immune response; optic placode formation involved in camera-type eye; transmembrane receptor protein tyrosine phosphatase signaling pathway

Research Articles on FRS2

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Product Notes

The FRS2 frs2 (Catalog #AAA9437286) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FRS2 (Phospho-Tyr436) Polyclonal Conjugated Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FRS2 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the FRS2 frs2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FRS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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