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Western Blot (WB) (Western blot analysis of CD7 on human CD7 recombinant protein using anti-CD7 antibody at 1/1, 000 dilution.)

Mouse anti-Human CD7 Monoclonal Antibody | anti-CD7 antibody

CD7 Antibody

Gene Names
CD7; GP40; TP41; Tp40; LEU-9
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
ProA affinity purified
Synonyms
CD7; Monoclonal Antibody; CD7 Antibody; CD7 antibody; CD7 antigen (p41) antibody; CD7 antigen antibody; CD7 molecule antibody; CD7_HUMAN antibody; GP40 antibody; LEU 9 antibody; LEU9 antibody; p41 protein antibody; T cell antigen CD7 antibody; T cell leukemia antigen antibody; T cell surface antigen Leu 9 antibody; T-cell antigen CD7 antibody; T-cell leukemia antigen antibody; T-cell surface antigen Leu-9 antibody; Tp 40 antibody; Tp40 antibody; TP41 antibody; anti-CD7 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone Number
F8-D4
Purity/Purification
ProA affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CD7 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:500-1:1000
IHC: 1:50-1:200
FC/FACS: 1:100-1:200
Immunogen
Recombinant protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.

Western Blot (WB)

(Western blot analysis of CD7 on human CD7 recombinant protein using anti-CD7 antibody at 1/1, 000 dilution.)

Western Blot (WB) (Western blot analysis of CD7 on human CD7 recombinant protein using anti-CD7 antibody at 1/1, 000 dilution.)

Western Blot (WB)

(Western blot analysis of CD7 on HEK293 (1) and CD7-hIgGFc transfected HEK293 (2) cell lysate using anti-CD7 antibody at 1/1, 000 dilution.)

Western Blot (WB) (Western blot analysis of CD7 on HEK293 (1) and CD7-hIgGFc transfected HEK293 (2) cell lysate using anti-CD7 antibody at 1/1, 000 dilution.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-CD7 antibody. Counter stained with hematoxylin.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-CD7 antibody. Counter stained with hematoxylin.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of Jurkat cells with CD7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of Jurkat cells with CD7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).)
Related Product Information for anti-CD7 antibody
CD7 (also designated T cell leukemia antigen) is a type I transmembrane glycoprotein that is expressed on pluripotential hemapoietic cells, most human thymocytes and some peripheral blood T cells. CD7 is a marker for pluripotential stem cell leukemias and T cell acute lymphocytic leukemia. A role for CD7 in the activation of T cells with g/d receptors has been suggested. CD8 T cells from patients infected with HIV-1 displayed profound down-modulation of CD7 expression as compared with healthy subjects. CD7 is among the pan-T-cell antigens down-regulated in acute infectious mononucleosis.
Product Categories/Family for anti-CD7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
924
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,409 Da
NCBI Official Full Name
T-cell antigen CD7
NCBI Official Synonym Full Names
CD7 molecule
NCBI Official Symbol
CD7
NCBI Official Synonym Symbols
GP40; TP41; Tp40; LEU-9
NCBI Protein Information
T-cell antigen CD7; CD7 antigen (p41); T-cell leukemia antigen; T-cell surface antigen Leu-9; p41 protein
UniProt Protein Name
T-cell antigen CD7
Protein Family
UniProt Gene Name
CD7
UniProt Entry Name
CD7_HUMAN

NCBI Description

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]

Uniprot Description

CD7: Not yet known.

Protein type: Membrane protein, integral; Immunoglobulin superfamily

Chromosomal Location of Human Ortholog: 17q25.2-q25.3

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: receptor activity

Biological Process: T cell activation; homeostasis of number of cells within a tissue; immune response; transmembrane receptor protein tyrosine kinase signaling pathway

Research Articles on CD7

Similar Products

Product Notes

The CD7 cd7 (Catalog #AAA9435293) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The CD7 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB: 1:500-1:1000 IHC: 1:50-1:200 FC/FACS: 1:100-1:200. Researchers should empirically determine the suitability of the CD7 cd7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD7, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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