SDS-Page
(Fig.SDS-PAGE analysis of Human CD7/GP40 protein)
CD7/GP40 recombinant protein
Human CD7/GP40 protein, His tag (Animal-Free)
Gene Names
CD7; GP40; TP41; Tp40; LEU-9
Purity
>95% as determined by SDS-PAGE
Synonyms
CD7/GP40; Human CD7/GP40 protein; His tag (Animal-Free); CD7 Molecule; T-Cell Leukemia Antigen; T-Cell Antigen CD7; TP41; T-Cell Surface Antigen Leu-9; CD7 Antigen (P41); P41 Protein; LEU-9; Tp40; CD7 Antigen 4; CD7; CD7/GP40 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
0.22um filtered protein solution is in PBS, pH7.4.
Sequence
Met1-Pro180
Endotoxin
<0.1 EU per ug of the protein as determined by the LAL method.
Protein Construction
Amino acid sequence derived from human CD7 protein (NP_006128.1, Met 1-Pro 180) was expressed with a polyhistidine tag at the C-terminus.
Protein Length
The recombinant human CD7/GP40 protein consists of 161 amino acids and predicts a molecular mass of 18 kD.The apparent molecular mass of the human CD7 is approximately 25-35kDa in SDS-PAGE under reducing conditions due to glycosylation.
Usage Notes
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD7/GP40 protein using the buffer we provided not less than 100ug/mL, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized human CD7/GP40 protein product should be stored desiccated below -20 degree C. Upon reconstitution, the protein should be stored at 4 degree C between 2-7 days and for future use below -20 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
SDS-Page
(Fig.SDS-PAGE analysis of Human CD7/GP40 protein)
SDS-Page
(Fig.SDS-PAGE analysis of Human CD7/GP40 protein)
Related Product Information for CD7/GP40 recombinant protein
Description: Recombinant Human CD7/GP40 protein expressed in HEK293Cells.
Background: The CD7 antigen is a member of the immunoglobulin superfamily that expresses on the surface of all thymocytes, a majority of mature T cells, and also natural killer cells. Interestingly, under physiological and different pathological conditions, the loss of CD7 antigen occurred in the subset of CD4+ memory T cells. The functions of the cell membrane CD7 antigen have been investigated in human mature T and NK cells, showing the direct involvement of this molecule in multiple effector functions related with activation, proliferation, production of cytokines and modification of adhesion properties. The CD7 glycoprotein is not only expressed by mature lymphoid cells, but also by early hematopoietic progenitors and several types of leukemias, suggesting a role of CD7 during hematopoiesis.
Background: The CD7 antigen is a member of the immunoglobulin superfamily that expresses on the surface of all thymocytes, a majority of mature T cells, and also natural killer cells. Interestingly, under physiological and different pathological conditions, the loss of CD7 antigen occurred in the subset of CD4+ memory T cells. The functions of the cell membrane CD7 antigen have been investigated in human mature T and NK cells, showing the direct involvement of this molecule in multiple effector functions related with activation, proliferation, production of cytokines and modification of adhesion properties. The CD7 glycoprotein is not only expressed by mature lymphoid cells, but also by early hematopoietic progenitors and several types of leukemias, suggesting a role of CD7 during hematopoiesis.
Product Categories/Family for CD7/GP40 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25,409 Da
NCBI Official Full Name
T-cell antigen CD7
NCBI Official Synonym Full Names
CD7 molecule
NCBI Official Symbol
CD7
NCBI Official Synonym Symbols
GP40; TP41; Tp40; LEU-9
NCBI Protein Information
T-cell antigen CD7; CD7 antigen (p41); T-cell leukemia antigen; T-cell surface antigen Leu-9; p41 protein
UniProt Protein Name
T-cell antigen CD7
UniProt Gene Name
CD7
UniProt Entry Name
CD7_HUMAN
NCBI Description
This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. [provided by RefSeq, Jul 2008]
Uniprot Description
CD7: Not yet known.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 17q25.2-q25.3
Cellular Component: membrane; plasma membrane; integral to membrane
Molecular Function: receptor activity
Biological Process: T cell activation; homeostasis of number of cells within a tissue; immune response; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on CD7/GP40
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Product Notes
The CD7/GP40 cd7 (Catalog #AAA9719000) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Pro18 0. It is sometimes possible for the material contained within the vial of "CD7/GP40, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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