Mouse anti-Human Golgin Subfamily A Member 5 Monoclonal Antibody | anti-GOLGA5 antibody

Golgin Subfamily A Member 5 Antibody

Cat. Num. AAA9434944

• Gene Names: GOLGA5; RFG5; GOLIM5; ret-II
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: ProA affinity purified
• Synonyms: Golgin Subfamily A Member 5; Monoclonal Antibody; Golgin Subfamily A Member 5 Antibody; Cell proliferation inducing gene 31 antibody; Cell proliferation-inducing gene 31 protein antibody; GOGA5_HUMAN antibody; GOLGA 5 antibody; GOLGA5 antibody; Golgi autoantigen golgin subfamily a 5 antibody; Golgi integral membrane protein 5 antibody; Golgin 84 antibody; Golgin A5 antibody; Golgin subfamily A member 5 antibody; Golgin-84 antibody; Golgin84 antibody; GOLIM 5 antibody; GOLIM5 antibody; Protein Ret-II antibody; PTC5 antibody; Ret fused gene 5 antibody; RET fused gene 5 protein antibody; Ret II antibody; Ret II protein antibody; RET-fused gene 5 protein antibody; RFG 5 antibody; RFG5 antibody; anti-GOLGA5 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Clone Number: 11-D7
• Purity/Purification: ProA affinity purified
• Form/Format: 1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Applicable Applications for anti-GOLGA5 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:1000; IHC: 1:100
• Immunogen: Recombinant protein
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C.

Western Blot (WB)

(Western blot analysis on Hela cell lysates using anti-GOLGA5 Mouse mAb.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin- embedded gastric cancer tissue using anti-GOLGA5 Mouse mAb.)

Related Product Information for anti-GOLGA5 antibody

Golgin subfamily A member 5 (GOLGA5) is a golgi apparatus membrane protein, highly expressed in seminiferous tubules and Leydig cells in testis. It is highly phosphorylated during mitosis. GOLGA5 is involved in maintaining Golgi structure and intra-Golgi retrograde transport. It stimulates the formation of Golgi stacks and ribbons. Defects in GOLGA5 are a cause of thyroid papillary carcinoma (TPC).

Product Categories/Family for anti-GOLGA5 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 30260188
• NCBI GeneID: 9950
• NCBI Accession #: NP_005104
• NCBI GenBank Nucleotide #: NM_005113.2
• UniProt Accession #: Q8TBA6; O95287; Q03962; Q2TS49; Q9UQQ7; C9JRU1
• Molecular Weight: Predicted: 64; 80 kDa; ; Observed: 65; 78 kDa
• NCBI Official Full Name: Golgin subfamily A member 5
• NCBI Official Synonym Full Names: golgin A5
• NCBI Official Symbol: GOLGA5
• NCBI Official Synonym Symbols: RFG5; GOLIM5; ret-II
• NCBI Protein Information: Golgin subfamily A member 5; golgin-84; RET-fused gene 5 protein; golgi integral membrane protein 5; golgi autoantigen, golgin subfamily a, 5; cell proliferation-inducing gene 31 protein
• UniProt Protein Name: Golgin subfamily A member 5
• Protein Family: Golgin subfamily
• UniProt Gene Name: GOLGA5
• UniProt Synonym Gene Names: RETII; RFG5
• UniProt Entry Name: GOGA5_HUMAN

NCBI Description

The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. [provided by RefSeq, Jul 2013]

Uniprot Description

GOLGA5: a member of the golgin family of proteins, whose members localize to the Golgi. Involved in regulating the architecture of the Golgi apparatus. A coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues. Highly phosphorylated during mitosis. Phosphorylation is barely detectable during interphase. Two splice variant isoforms have been described.

Protein type: Membrane protein, integral; Cytoskeletal

Chromosomal Location of Human Ortholog: 14q32.12

Cellular Component: Golgi membrane; Golgi apparatus; Golgi cisterna; cis-Golgi network; membrane; integral to membrane

Molecular Function: protein homodimerization activity; Rab GTPase binding

Biological Process: Golgi organization and biogenesis; Golgi vesicle transport

Disease: Thyroid Carcinoma, Papillary