Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SIVA1 antibody.)
Rabbit anti-Human SIVA1 Polyclonal Antibody | anti-SIVA1 antibody
SIVA1 Polyclonal Antibody
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SIVA1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of various cell lines, using SIVA1 antibody.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described. [provided by RefSeq, Jul 2008]
Uniprot Description
Siva: a proapoptotic protein. Associates with CD27, a member of the tumor necrosis factor receptor family. Two alternatively spliced isoforms have been described. Isoform 1 but not isoform 2 may induce TNFRSF7/CD27 mediated apoptosis. Isoform 1 inhibits Bcl-xL anti-apoptotic activity.
Protein type: Apoptosis
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; mitochondrion; cytoplasm; nucleus
Molecular Function: viral receptor activity; protein binding; zinc ion binding; metal ion binding; CD27 receptor binding
Biological Process: entry of virus into host cell; inhibition of NF-kappaB transcription factor; activated T cell apoptosis
Research Articles on SIVA1
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Product Notes
The SIVA1 siva1 (Catalog #AAA9433843) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIVA1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIVA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SIVA1 siva1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIVA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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