Rat Corticotropin-releasing factor receptor 1 ELISA Kit | Crhr1 elisa kit
Rat Corticotropin-releasing factor receptor 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the G-protein coupled receptor family. The encoded protein is a receptor for corticotropin-releasing factor (CRH) and urocortin (UCN). The interaction of this protein with CRH and UCN triggers G-protein coupled signaling. This protein plays a pivotal role in mediating the CRH-elicited effects in depression and anxiety. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Description
CRF-R1: a G-protein coupled receptor that specifically binds corticotropin-releasing hormone, a potent mediator of endocrine, autonomic, behavioral, and immune responses to stress. Four splice-variant isoforms have been described.
Protein type: GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 10q32.1
Cellular Component: apical part of cell; cell soma; dendrite; dendritic spine; integral to membrane; intrinsic to plasma membrane; membrane; multivesicular body; plasma membrane; trans-Golgi network; vesicle
Molecular Function: corticotrophin-releasing factor receptor activity; corticotropin-releasing hormone binding; corticotropin-releasing hormone receptor activity; G-protein alpha-subunit binding; G-protein coupled receptor activity; peptide binding; protein binding; protein complex binding
Biological Process: adrenal gland development; adrenocorticotropin hormone secretion; behavioral response to cocaine; behavioral response to ethanol; behavioral response to pain; elevation of cytosolic calcium ion concentration; epithelial cell differentiation; fear response; feeding behavior; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); general adaptation syndrome, behavioral process; hypothalamus development; memory; negative regulation of epinephrine secretion; neuropeptide signaling pathway; positive regulation of cAMP biosynthetic process; positive regulation of mast cell degranulation; regulation of synaptic plasticity; response to electrical stimulus; response to hypoxia; visual learning
Research Articles on Crhr1
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Product Notes
The Rat Crhr1 crhr1 (Catalog #AAA9426710) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9426710 ELISA Kit recognizes Rat Crhr1. It is sometimes possible for the material contained within the vial of "Corticotropin-releasing factor receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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