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Typical Testing Data/Standard Curve (for reference only)

Rat Corticotropin Releasing Hormone Receptor 1 (CRHR1) ELISA Kit | CRHR1 elisa kit

Rat Corticotropin Releasing Hormone Receptor 1 (CRHR1) ELISA Kit

Gene Names
Crhr1; CRFR1; CRH-R 1
Reactivity
Rat
Synonyms
Corticotropin Releasing Hormone Receptor 1 (CRHR1); Rat Corticotropin Releasing Hormone Receptor 1 (CRHR1) ELISA Kit; CRF-R; CRF1; CRFR1; CRH-R1h; CRHR; CRHR1f; Corticotropin-releasing factor receptor 1; CRHR1 elisa kit
Ordering
For Research Use Only!
Reactivity
Rat
Sequence Length
415
Samples
Tissue homogenates, cell lysates and other biological fluids.
Assay Type
Sandwich
Detection Range
0.312-20ng/mL
Sensitivity
0.123ng/mL
Intra Assay
CV<10%
Inter Assay
CV<12%
Preparation and Storage
For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,842 Da
NCBI Official Full Name
corticotropin-releasing factor receptor 1 isoform 1
NCBI Official Synonym Full Names
corticotropin releasing hormone receptor 1
NCBI Official Symbol
Crhr1
NCBI Official Synonym Symbols
CRFR1; CRH-R 1
NCBI Protein Information
corticotropin-releasing factor receptor 1
UniProt Protein Name
Corticotropin-releasing factor receptor 1
UniProt Gene Name
Crhr1
UniProt Synonym Gene Names
Crhr; CRF-R-1; CRF-R1; CRFR-1; CRH-R-1; CRH-R1

NCBI Description

This gene encodes a member of the G-protein coupled receptor family. The encoded protein is a receptor for corticotropin-releasing factor (CRH) and urocortin (UCN). The interaction of this protein with CRH and UCN triggers G-protein coupled signaling. This protein plays a pivotal role in mediating the CRH-elicited effects in depression and anxiety. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]

Uniprot Description

G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

Research Articles on CRHR1

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Product Notes

The Rat CRHR1 crhr1 (Catalog #AAA453497) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA453497 ELISA Kit recognizes Rat CRHR1. It is sometimes possible for the material contained within the vial of "Corticotropin Releasing Hormone Receptor 1 (CRHR1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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