U2 small nuclear ribonucleoprotein B Recombinant Protein | RU2B recombinant protein

Recombinant Human U2 small nuclear ribonucleoprotein B

Cat. Num. AAA9421043

• Gene Names: SNRPB2; Msl1; U2B''
• Reactivity: Human
• Purity: Greater than 90% as determined by SDS-PAGE.
• Synonyms: U2 small nuclear ribonucleoprotein B; Recombinant Human U2 small nuclear ribonucleoprotein B; RU2B recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 90% as determined by SDS-PAGE.
• Form/Format: 20mM Tris-HCl based buffer, pH8.0
• Sequence Positions: Full Length, 1-225aa

• Tag Info: His-SUMO-tag
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Related Product Information for RU2B recombinant protein

Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds st loop IV of U2 snRNA only in presence of the U2A' protein.

NCBI and Uniprot Product Information

• NCBI GI #: 4507123
• NCBI GeneID: 6629
• NCBI Accession #: NP_003083.1
• NCBI GenBank Nucleotide #: NM_003092.4
• UniProt Accession #: P08579; Q9UJD4; B2R7J3; D3DW21
• Molecular Weight: 41.47kD
• NCBI Official Full Name: U2 small nuclear ribonucleoprotein B''
• NCBI Official Synonym Full Names: small nuclear ribonucleoprotein polypeptide B2
• NCBI Official Symbol: SNRPB2
• NCBI Official Synonym Symbols: Msl1; U2B''
• NCBI Protein Information: U2 small nuclear ribonucleoprotein B''
• UniProt Protein Name: U2 small nuclear ribonucleoprotein B''
• Protein Family: U2 small nuclear ribonucleoprotein
• UniProt Gene Name: SNRPB2
• UniProt Synonym Gene Names: U2 snRNP B''

NCBI Description

The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

snRNP B2: a small nuclear ribonucleoprotein. Involved in pre-mRNA splicing. This protein is associated with snRNP U2. It binds stem loop IV of U2 snRNA only in presence of the A' protein.

Protein type: RNA processing; RNA splicing; RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 20p12.1

Cellular Component: fibrillar center; nuclear speck; nucleoplasm; snRNP U1; snRNP U2; spliceosome

Molecular Function: protein binding; U1 snRNA binding

Biological Process: nuclear mRNA splicing, via spliceosome