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Western Blot (WB) (Western blot analysis of PIG-Y in A-20 cell lysate with PIG-Y antibody at 2 ug/mL.)

Rabbit anti-Human, Mouse PIG-Y Polyclonal Antibody | anti-PIG-Y antibody

PIG-Y Antibody

Gene Names
PYURF; PREY
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
PIG-Y; Polyclonal Antibody; PIG-Y Antibody; Phosphatidylinositol glycan anchor biosynthesis class Y; PreY; PIGY; anti-PIG-Y antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
This antibody only detects isoform 1 of PIG-Y.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
114
Applicable Applications for anti-PIG-Y antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide near the carboxy terminus of human PIG-Y.
Target Name
PIG-Y
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of PIG-Y in A-20 cell lysate with PIG-Y antibody at 2 ug/mL.)

Western Blot (WB) (Western blot analysis of PIG-Y in A-20 cell lysate with PIG-Y antibody at 2 ug/mL.)

Immunohistochemistry (IHC)

(Immunohistochemistry of PIGY in human spleen tissue with PIGY antibody at 2.5 ug/mL.)

Immunohistochemistry (IHC) (Immunohistochemistry of PIGY in human spleen tissue with PIGY antibody at 2.5 ug/mL.)
Related Product Information for anti-PIG-Y antibody
Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA.
Product Categories/Family for anti-PIG-Y antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12,655 Da
NCBI Official Full Name
protein preY, mitochondrial
NCBI Official Synonym Full Names
PIGY upstream reading frame
NCBI Official Symbol
PYURF
NCBI Official Synonym Symbols
PREY
NCBI Protein Information
protein preY, mitochondrial
UniProt Protein Name
Protein preY, mitochondrial
UniProt Gene Name
PYURF
UniProt Synonym Gene Names
PREY
UniProt Entry Name
PREY_HUMAN

NCBI Description

The product of this gene, which is well-conserved, is encoded by the same bicistronic transcript that encodes phosphatidylinositol glycan anchor biosynthesis, class Y, but the two proteins are unrelated. This gene represents the protein encoded by the upstream open reading frame, while the protein encoded by the downstream open reading frame is represented by GeneID:84992. [provided by RefSeq, Aug 2012]

Uniprot Description

PYURF: Belongs to the PREY family

Chromosomal Location of Human Ortholog: 4q

Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; mitochondrion

Molecular Function: protein binding

Biological Process: positive regulation of metabolic process; GPI anchor biosynthetic process

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Product Notes

The PIG-Y pyurf (Catalog #AAA9414487) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIG-Y Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PIG-Y can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the PIG-Y pyurf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIG-Y, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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