Rabbit anti-Human VAM1 Polyclonal Antibody | anti-VAM1 antibody

VAM1 antibody

Cat. Num. AAA9413015

• Gene Names: MPP6; VAM1; p55T; PALS2; VAM-1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Purified by antigen-affinity chromatography.
• Synonyms: VAM1; Polyclonal Antibody; VAM1 antibody; anti-VAM1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified by antigen-affinity chromatography.
• Form/Format: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
• Sequence Length: 540

• Applicable Applications for anti-VAM1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500-1:3000; Immunohistochemistry: 1:100-1:250
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of VAM1
• Target Name: VAM1
• Preparation and Storage: Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.

Testing Data

(Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE Primary antibody diluted at 1: 1000)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Colon, using VAM1 antibody at 1: 100 dilution.)

Related Product Information for anti-VAM1 antibody

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM]

Product Categories/Family for anti-VAM1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 21361598
• NCBI GeneID: 51678
• NCBI Accession #: NP_057531
• NCBI GenBank Nucleotide #: NM_016447.3
• Molecular Weight: 61,117 Da
• NCBI Official Full Name: MAGUK p55 subfamily member 6
• NCBI Official Synonym Full Names: membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
• NCBI Official Symbol: MPP6
• NCBI Official Synonym Symbols: VAM1; p55T; PALS2; VAM-1
• NCBI Protein Information: MAGUK p55 subfamily member 6
• UniProt Protein Name: MAGUK p55 subfamily member 6
• UniProt Gene Name: MPP6
• UniProt Synonym Gene Names: VAM1; VAM-1
• UniProt Entry Name: MPP6_HUMAN

NCBI Description

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM, Mar 2008]

Uniprot Description

VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7p15

Cellular Component: membrane; plasma membrane

Molecular Function: protein binding; PDZ domain binding

Biological Process: protein complex assembly