Rabbit MPP6 Polyclonal Antibody | anti-MPP6 antibody

MPP6 Polyclonal Antibody

Cat. Num. AAA3009646

• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: MPP6; Polyclonal Antibody; MPP6 Polyclonal Antibody; VAM1; p55T; PALS2; VAM-1; anti-MPP6 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: MPP6 polyclonal antibody detects endogenous levels of MPP6 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 540

• Applicable Applications for anti-MPP6 antibody: Western Blot (WB)
• Application Notes: WB: 1:1000-1:2000
• Immunogen: Recombinant protein of human MPP6
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cells, using MPP6 antibody.)

Related Product Information for anti-MPP6 antibody

Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001

NCBI and Uniprot Product Information

• NCBI GI #: 119614217
• UniProt Accession #: Q9NZW5
• Molecular Weight: ~ 61kDa
• NCBI Official Full Name: membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6), isoform CRA_c
• UniProt Protein Name: MAGUK p55 subfamily member 6
• Protein Family: MAGUK p55 subfamily
• UniProt Gene Name: MPP6
• UniProt Synonym Gene Names: VAM1; VAM-1
• UniProt Entry Name: MPP6_HUMAN

Uniprot Description

VAM-1: a membrane-associated of the MAGUK family. Interacts with Lin7, which localizes to postsynaptic densities of neurons and epithelial cell-cell junctions.

Protein type: Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 7p15

Cellular Component: membrane; plasma membrane

Molecular Function: protein binding; PDZ domain binding

Biological Process: protein complex assembly