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Testing Data (Sample (30 ug of whole cell lysate) A: A431 B: Raji 7.5% SDS PAGE diluted at 1:1000)

Rabbit anti-Human CPEB1 Polyclonal Antibody | anti-CPEB1 antibody

CPEB1 Antibody

Gene Names
CPEB1; CPEB; CPEB-1; h-CPEB; CPE-BP1; hCPEB-1
Reactivity
Human
Applications
Western Blot
Purity
Antibodies were purified by antigen-affinity chromatography.
Synonyms
CPEB1; Polyclonal Antibody; CPEB1 Antibody; CEBP antibody; CPE-BP1 antibody; CPEB antibody; FLJ13203 antibody; MGC34136 antibody; MGC60106 antibody; CPEB1 antibody; cytoplasmic polyadenylation element-binding protein 1 antibody; h-CEBP antibody; CPE-binding protein 1 antibody; hCPEB-1 antibody; cyt; anti-CPEB1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total CPEB1 protein.
Purity/Purification
Antibodies were purified by antigen-affinity chromatography.
Form/Format
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration
0.29 mg/ml (varies by lot)
Sequence Length
491
Applicable Applications for anti-CPEB1 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500-1:3000
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region within amino acids 505 and 566 of CPEB1.
Target Name
CPEB1
Preparation and Storage
Store at -20 degree C

Testing Data

(Sample (30 ug of whole cell lysate) A: A431 B: Raji 7.5% SDS PAGE diluted at 1:1000)

Testing Data (Sample (30 ug of whole cell lysate) A: A431 B: Raji 7.5% SDS PAGE diluted at 1:1000)
Related Product Information for anti-CPEB1 antibody
This gene encodes a member of the cytoplasmic polyadenylation element (CPE) binding protein family. This highly conserved protein binds to a specific RNA sequence called the CPE found in the 3' UTR of some mRNAs. Similar proteins in Xenopus and mouse function to induce cytoplasmic polyadenylation of dormant mRNAs with short polyA tails, resulting in their translation. Members of this protein family regulate translation of cyclin B1 during embryonic cell divisions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Product Categories/Family for anti-CPEB1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,635 Da
NCBI Official Full Name
cytoplasmic polyadenylation element-binding protein 1 isoform 2
NCBI Official Synonym Full Names
cytoplasmic polyadenylation element binding protein 1
NCBI Official Symbol
CPEB1
NCBI Official Synonym Symbols
CPEB; CPEB-1; h-CPEB; CPE-BP1; hCPEB-1
NCBI Protein Information
cytoplasmic polyadenylation element-binding protein 1
UniProt Protein Name
Cytoplasmic polyadenylation element-binding protein 1
UniProt Gene Name
CPEB1
UniProt Synonym Gene Names
CPEB; CPE-BP1; CPE-binding protein 1; h-CPEB; hCPEB-1
UniProt Entry Name
CPEB1_HUMAN

NCBI Description

This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Uniprot Description

CPEB: cytoplasmic polyadenylation element binding protein 1. Binds to the protein CPE and drives its polyadenylation. Activated by the protein kinase AurA. Insulin and progesterone stimulate AurA-catalyzed phosphorylation of CPEB in oocytes. Neuronal CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia.

Protein type: RNA-binding; Translation

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: postsynaptic membrane; postsynaptic density; dendrite; cytoplasm; cell junction; nucleus

Molecular Function: metal ion binding; translation repressor activity, nucleic acid binding; nucleotide binding

Biological Process: synaptonemal complex assembly; cellular response to insulin stimulus; mRNA processing; regulation of neuronal synaptic plasticity

Research Articles on CPEB1

Similar Products

Product Notes

The CPEB1 cpeb1 (Catalog #AAA9412153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CPEB1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CPEB1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500-1:3000. Researchers should empirically determine the suitability of the CPEB1 cpeb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CPEB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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