Rabbit anti-Human, Mouse NOD6 Polyclonal Antibody | anti-NOD6 antibody

NOD6 Antibody

Cat. Num. AAA9408817

• Gene Names: NLRP9; NOD6; NALP9; PAN12; CLR19.1
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity chromatography purified via peptide column
• Synonyms: NOD6; Polyclonal Antibody; NOD6 Antibody; Nucleotide-binding oligomerization domain containing 6; NLRP6; NALP9; PAN12 CLR 19.1; anti-NOD6 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 991

• Applicable Applications for anti-NOD6 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 14 amino acid peptide near the amino terminus of human NOD6.
• Target Name: NOD6
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of NOD6 in EL4 cell lysate with NOD6 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.)

Immunohistochemistry (IHC)

(Immunohistochemistry of NOD6 in human testis tissue with NOD6 antibody at 10 ug/mL.)

Related Product Information for anti-NOD6 antibody

NOD6, also known as NALP9, is a member of the NALP family, a group of proteins that typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD) and are involved in inflammation and innate immune defense. The bovine NOD6, which has 76% homology to its human counterpart, has been suggested to be an oocyte marker gene. In adult tissues, NALP9 mRNA is expressed exclusively in ovary and testis.

Product Categories/Family for anti-NOD6 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 33519450
• NCBI GeneID: 338321
• NCBI Accession #: NP_789790.2
• NCBI GenBank Nucleotide #: NM_176820.3
• UniProt Accession #: Q7RTR0; Q86W27; B2RN12
• Molecular Weight: 112,593 Da
• NCBI Official Full Name: NACHT, LRR and PYD domains-containing protein 9
• NCBI Official Synonym Full Names: NLR family, pyrin domain containing 9
• NCBI Official Symbol: NLRP9
• NCBI Official Synonym Symbols: NOD6; NALP9; PAN12; CLR19.1
• NCBI Protein Information: NACHT, LRR and PYD domains-containing protein 9
• UniProt Protein Name: NACHT, LRR and PYD domains-containing protein 9
• UniProt Gene Name: NLRP9
• UniProt Synonym Gene Names: NALP9; NOD6; PAN12
• UniProt Entry Name: NALP9_HUMAN

NCBI Description

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

Uniprot Description

NLRP9: Involved in inflammation (Potential). Belongs to the NLRP family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.42

Cellular Component: cytoplasm

Molecular Function: ATP binding