Western Blot (WB)
(Western blot analysis of ECRG4 in HeLa cell lysate with ECRG4 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit ECRG4 Polyclonal Antibody | anti-ECRG4 antibody
ECRG4 Antibody
Gene Names
SPINK7; ECG2; ECRG2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
ECRG4; Polyclonal Antibody; ECRG4 Antibody; Esophageal cancer-related gene 4 protein; Augurin; C2orf40; anti-ECRG4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
ECRG4 antibody is predicted to not cross-react with other ECRG family members.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Sequence Length
85
Applicable Applications for anti-ECRG4 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 20 amino acid peptide near the carboxy terminus of human ECRG4.
Target Name
ECRG4
Preparation and Storage
Can be stored at -20°C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of ECRG4 in HeLa cell lysate with ECRG4 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of ECRG4 in HeLa cell lysate with ECRG4 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-ECRG4 antibody
The esophageal cancer-related gene 4 (ECRG4), also known as Augurin, was identified through differential display screening between esophageal cancer and normal tissue. Hypermethylation of CpG sites in the ECRG4 promoter correlate with ECRG4 downregulation in numerous esophageal squamous cell carcinoma tissues.. In transfected cells, overexpression of ECRG4 induced G1 arrest, dephosphorylation of Rb and decreased expression of cyclins D1 and D3. Increased expression of ECRG4 in aged mouse brain is observed compared with young mouse brain. The increased ECRG4 level was accompanied by elevated senescence-associated acidic beta-galactosidase activity, suggesting that ECRG4 is involved in cellular differentiation and senescence.
Product Categories/Family for anti-ECRG4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Esophagus cancer-related gene-2
NCBI Official Synonym Full Names
serine peptidase inhibitor, Kazal type 7 (putative)
NCBI Official Symbol
SPINK7
NCBI Official Synonym Symbols
ECG2; ECRG2
NCBI Protein Information
serine protease inhibitor Kazal-type 7
UniProt Protein Name
Serine protease inhibitor Kazal-type 7
UniProt Gene Name
SPINK7
UniProt Synonym Gene Names
ECG2; ECRG-2
UniProt Entry Name
ISK7_HUMAN
Uniprot Description
SPINK7: Probable serine protease inhibitor.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: extracellular region
Molecular Function: serine-type endopeptidase inhibitor activity; protein binding
Research Articles on ECRG4
Similar Products
Product Notes
The ECRG4 spink7 (Catalog #AAA9408781) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ECRG4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ECRG4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the ECRG4 spink7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ECRG4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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