Rabbit anti-Human ELF1 Polyclonal Antibody | anti-ELF1 antibody

ELF1 Antibody

Cat. Num. AAA9407968

• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: ELF1; Polyclonal Antibody; ELF1 Antibody; E74-like factor 1; ETS-related transcription factor Elf-1; anti-ELF1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total ELF1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 595

• Applicable Applications for anti-ELF1 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500~1:3000; Immunofluorescence: 1:100~1:500
• Immunogen Type: Peptide
• Immunogen Description: Synthesized peptide derived from C-terminal of human ELF1.
• Target Name: ELF1
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from 293 cells and HuvEc cells, using ELF1 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of A549 cells, using ELF1 antibody.)

Related Product Information for anti-ELF1 antibody

Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.Leiden J.M., J. Virol. 66:5890-5897(1992).Thompson C.B., Mol. Cell. Biol. 12:1043-1053(1992).Wang C.Y., Science 260:1330-1335(1993).

Product Categories/Family for anti-ELF1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 223941929
• NCBI GeneID: 1997
• NCBI Accession #: NP_001138825.1
• NCBI GenBank Nucleotide #: NM_001145353.1
• UniProt Accession #: P32519; Q8N6F6; Q9UDE1; B4E2I5; E9PDQ9
• Molecular Weight: 64,929 Da
• NCBI Official Full Name: ETS-related transcription factor Elf-1 isoform b
• NCBI Official Synonym Full Names: E74-like factor 1 (ets domain transcription factor)
• NCBI Official Symbol: ELF1
• NCBI Protein Information: ETS-related transcription factor Elf-1
• UniProt Protein Name: ETS-related transcription factor Elf-1
• Protein Family: ETS-related transcription factor
• UniProt Gene Name: ELF1
• UniProt Entry Name: ELF1_HUMAN

NCBI Description

This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]

Uniprot Description

Elf-1: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. Belongs to the ETS family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 13q13

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; regulation of cytokine production