Rabbit anti-Human BRWD1 Polyclonal Antibody | anti-BRWD1 antibody

BRWD1 Antibody

Cat. Num. AAA9406381

• Gene Names: BRWD1; N143; WDR9; C21orf107
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: BRWD1; Polyclonal Antibody; BRWD1 Antibody; N143; WDR9; C21orf107; anti-BRWD1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total BRWD1 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.5 mg/ml (varies by lot)
• Sequence Length: 120

• Applicable Applications for anti-BRWD1 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:25-1:100
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to residues near the N terminal of human bromodomain and WD repeat domain containing 1
• Target Name: BRWD1
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25.)

Related Product Information for anti-BRWD1 antibody

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.

Product Categories/Family for anti-BRWD1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 55956930
• NCBI GeneID: 54014
• NCBI Accession #: NP_001007247.1
• NCBI GenBank Nucleotide #: NM_001007246.2
• UniProt Accession #: Q9NSI6; O43721; Q5R2V0; Q5R2V1; Q6P2D1; Q8TCV3; Q96QG9; Q96QH0; Q9NUK1; C9JK25
• Molecular Weight: 13,558 Da
• NCBI Official Full Name: bromodomain and WD repeat-containing protein 1 isoform C
• NCBI Official Synonym Full Names: bromodomain and WD repeat domain containing 1
• NCBI Official Symbol: BRWD1
• NCBI Official Synonym Symbols: N143; WDR9; C21orf107
• NCBI Protein Information: bromodomain and WD repeat-containing protein 1
• UniProt Protein Name: Bromodomain and WD repeat-containing protein 1
• Protein Family: Bromodomain and WD repeat-containing protein
• UniProt Gene Name: BRWD1
• UniProt Synonym Gene Names: C21orf107; WDR9
• UniProt Entry Name: BRWD1_HUMAN

NCBI Description

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]

Uniprot Description

May be a transcriptional activator. May be involved in chromatin remodeling (). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.