Rabbit anti-Human SLC25A1 Polyclonal Antibody | anti-SLC25A1 antibody

SLC25A1 Antibody

Cat. Num. AAA9404841

• Gene Names: SLC25A1; CTP; SEA; D2L2AD; SLC20A3
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Antigen affinity purification.
• Synonyms: SLC25A1; Polyclonal Antibody; SLC25A1 Antibody; CTP; SEA; D2L2AD; SLC20A3; anti-SLC25A1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total SLC25A1 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 1.3 mg/ml (varies by lot)
• Sequence Length: 311

• Applicable Applications for anti-SLC25A1 antibody: Immunohistochemistry (IHC)
• Application Notes: Immunohistochemistry: 1:25-1:100
• Immunogen Type: Protein
• Immunogen Description: Fusion protein corresponding to residues near the N terminal of human solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
• Target Name: SLC25A1
• Preparation and Storage: Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/25.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/25.)

Related Product Information for anti-SLC25A1 antibody

This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria.

Product Categories/Family for anti-SLC25A1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 21389315
• NCBI GeneID: 6576
• NCBI Accession #: NP_005975.1
• NCBI GenBank Nucleotide #: NM_005984.4
• UniProt Accession #: P53007; Q9BSK6; A8K8E8
• Molecular Weight: 34,013 Da
• NCBI Official Full Name: tricarboxylate transport protein, mitochondrial isoform a
• NCBI Official Synonym Full Names: solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
• NCBI Official Symbol: SLC25A1
• NCBI Official Synonym Symbols: CTP; SEA; D2L2AD; SLC20A3
• NCBI Protein Information: tricarboxylate transport protein, mitochondrial
• UniProt Protein Name: Tricarboxylate transport protein, mitochondrial
• UniProt Gene Name: SLC25A1
• UniProt Synonym Gene Names: SLC20A3; CTP
• UniProt Entry Name: TXTP_HUMAN

NCBI Description

This gene encodes a member of the mitochondrial carrier subfamily of solute carrier proteins. Members of this family include nuclear-encoded transporters that translocate small metabolites across the mitochondrial membrane. This protein regulates the movement of citrate across the inner membranes of the mitochondria. Mutations in this gene have been associated with combined D-2- and L-2-hydroxyglutaric aciduria. Pseudogenes of this gene have been identified on chromosomes 7, 11, 16, and 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Uniprot Description

SLC25A1: Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. Belongs to the mitochondrial carrier family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family; Mitochondrial

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: mitochondrial inner membrane; integral to membrane; nucleus

Molecular Function: citrate transmembrane transporter activity

Biological Process: citrate transport; carbohydrate metabolic process; glucose metabolic process; triacylglycerol biosynthetic process; pathogenesis; cellular lipid metabolic process; transmembrane transport; gluconeogenesis

Disease: Combined D-2- And L-2-hydroxyglutaric Aciduria