Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse bladder tissue and 293T cell Amount of lysate: 40ug per lane Primary antibody: 1/930 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)
Rabbit CRELD1 Polyclonal Antibody | anti-CRELD1 antibody
CRELD1 Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse bladder tissue and 293T cell Amount of lysate: 40ug per lane Primary antibody: 1/930 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)
Testing Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse bladder tissue and 293T cell Amount of lysate: 40ug per lane Primary antibody: 1/930 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/40.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of a subfamily of epidermal growth factor-related proteins. The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain. This protein may function as a cell adhesion molecule. Mutations in this gene are the cause of atrioventricular septal defect. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
Uniprot Description
CRELD1: Defects in CRELD1 may be the cause of susceptibility to atrioventricular septal defect type 2 (AVSD2). AVSD is a spectrum of cardiac malformations that result in a persistent common atrioventricular canal. The complete form of AVSD involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum. A less severe form, known as partial AVSD or ostium primum atrial septal defect has a deficiency of the atrial septum. Complete AVSD are clinically apparent at birth, whereas less severe forms, such as an isolated cleft mitral valve or small defects of the atrial or ventricular septa may go undetected. Belongs to the CRELD family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Cell adhesion
Chromosomal Location of Human Ortholog: 3p25.3
Cellular Component: integral to membrane
Molecular Function: calcium ion binding
Disease: Atrioventricular Septal Defect, Susceptibility To, 2
Research Articles on CRELD1
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Product Notes
The CRELD1 creld1 (Catalog #AAA9403779) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRELD1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CRELD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the CRELD1 creld1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRELD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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