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Western Blot (WB) (Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 ug/ml and (B) 0.5 ug/mL.)

Rabbit anti-Human, Mouse ZIMP7 Polyclonal Antibody | anti-ZIMP7 antibody

ZIMP7 Antibody

Gene Names
ZMIZ2; NET27; ZIMP7; hZIMP7; TRAFIP20
Reactivity
Human, Mouse
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
ZIMP7; Polyclonal Antibody; ZIMP7 Antibody; Zinc finger MIZ-type containing 2; ZMIZ2; TRAFIP20; PIAS-like protein Zimp7; anti-ZIMP7 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
862
Applicable Applications for anti-ZIMP7 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the center of human ZIMP7.
Target Name
ZIMP7
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 ug/ml and (B) 0.5 ug/mL.)

Western Blot (WB) (Western blot analysis of ZIMP7 in A20 cell lysate with ZIMP7 antibody at (A) 0.25 ug/ml and (B) 0.5 ug/mL.)
Related Product Information for anti-ZIMP7 antibody
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Product Categories/Family for anti-ZIMP7 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
91,112 Da
NCBI Official Full Name
zinc finger MIZ domain-containing protein 2 isoform 3
NCBI Official Synonym Full Names
zinc finger, MIZ-type containing 2
NCBI Official Symbol
ZMIZ2
NCBI Official Synonym Symbols
NET27; ZIMP7; hZIMP7; TRAFIP20
NCBI Protein Information
zinc finger MIZ domain-containing protein 2
UniProt Protein Name
Zinc finger MIZ domain-containing protein 2
UniProt Gene Name
ZMIZ2
UniProt Synonym Gene Names
KIAA1886; ZIMP7
UniProt Entry Name
ZMIZ2_HUMAN

NCBI Description

ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010]

Uniprot Description

ZIMP7: Increases ligand-dependent transcriptional activity of AR and other nuclear hormone receptors. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleoplasm; mitochondrion; nuclear replication fork; nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor transcription coactivator activity; zinc ion binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter

Research Articles on ZIMP7

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Product Notes

The ZIMP7 zmiz2 (Catalog #AAA9402297) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZIMP7 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ZIMP7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the ZIMP7 zmiz2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZIMP7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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