Plant Phosphodiesterase 4D, cAMP Specific (PDE4D) ELISA Kit | PDE4D elisa kit
Plant Phosphodiesterase 4D, cAMP Specific (PDE4D) ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
PDE4D: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1). Isoform 5, isoform N3 and isoform 12 bind GNB2L1 via their unique N-terminus. Binds ARRB2. Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle. Inhibited by rolipram. Activated by phosphatidic acid. Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. 12 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.4.53; Nucleotide Metabolism - purine; Phosphodiesterase
Cellular Component: centrosome; voltage-gated calcium channel complex
Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; ATPase binding; protein binding
Biological Process: aging; cAMP catabolic process; leukocyte migration; multicellular organism growth; negative regulation of heart contraction; negative regulation of peptidyl-serine phosphorylation; neutrophil chemotaxis; regulation of cAMP metabolic process; regulation of heart rate; smooth muscle contraction
Research Articles on PDE4D
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Product Notes
The Plant PDE4D pde4d (Catalog #AAA9381800) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9381800 ELISA Kit recognizes Plant PDE4D. It is sometimes possible for the material contained within the vial of "Phosphodiesterase 4D, cAMP Specific (PDE4D), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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