Western Blot (WB)
Rabbit PDE4D7 Polyclonal Antibody | anti-PDE4D7 antibody
PDE4D7 Antibody
Gene Names
Pde4d; Dpde3; 9630011N22Rik
Reactivity
Chicken, Mouse, Rat
Applications
ELISA, Immunoprecipitation, Western Blot
Synonyms
PDE4D7; Polyclonal Antibody; PDE4D7 Antibody; DPDE3; HSPDE4D; PDE43; PDE4D; Phosphodiesterase 4D; Phosphodiesterase 4D cAMP-specific antibody; anti-PDE4D7 antibody
Host
Rabbit
Reactivity
Chicken, Mouse, Rat
Clonality
Polyclonal
Specificity
This antibody does not cross react with other PDE4D variants including PDE4D1, PDE4D2, PDE4D3, PDE4D4, PDE4D5. It also does not cross react with other PDE family members including PDE4A, PDE4B or PDE4C.
Form/Format
Affinity Purified
Concentration
0.2 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
2554
Applicable Applications for anti-PDE4D7 antibody
ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB)
Application Notes
Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500
ELISA: 1:10,000
Immunoprecipitation: 1:150
Western Blot: 1:500
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PDE4D7 variant.
Expression
Expressed in brain (at protein level). Isoform 7 is detected in heart, brain, lung, kidney and testis.
Molecular Function
Hydrolase, 3', 5'-cyclic-nucleotide phosphodiesterase activity, ATPase binding
Structure
Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Binds ARRB2. Interacts with PDE4DIP (By similarity). Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1). Interacts (via N-terminal region) with SHANK2 (via proline-rich region); the interaction is increased in a PKA-dependent manner.
Subcellular Location
Cytoplasm. Membrane. Cytoplasm degree cytoskeleton. Cytoplasm degree cytoskeleton degree microtubule organizing center degree centrosome. Apical cell membrane
Preparation and Storage
-20 degree C for long term storage
Western Blot (WB)
Western Blot (WB)
Related Product Information for anti-PDE4D7 antibody
Affinity Purified cAMP-specific phosphodiesterase PDE4D7 Antibody
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Product Categories/Family for anti-PDE4D7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
66,394 Da
NCBI Official Full Name
Mus musculus cAMP-specific phosphodiesterase PDE4D7 (Pde4d) mRNA, complete cds; alternatively spliced
NCBI Official Synonym Full Names
phosphodiesterase 4D, cAMP specific
NCBI Official Symbol
Pde4d
NCBI Official Synonym Symbols
Dpde3; 9630011N22Rik
NCBI Protein Information
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
UniProt Protein Name
cAMP-specific 3',5'-cyclic phosphodiesterase 4D
UniProt Gene Name
Pde4d
UniProt Entry Name
PDE4D_MOUSE
Uniprot Description
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Research Articles on PDE4D7
Similar Products
Product Notes
The PDE4D7 pde4d (Catalog #AAA543532) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE4D7 Antibody reacts with Chicken, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE4D7 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB). Dot Blot: 1:10,000 ELISA: 1:10,000 Immunoprecipitation: 1:150 Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE4D7 pde4d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE4D7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
