Pigeon MORC Family CW-Type Zinc Finger Protein 3 (MORC3) ELISA Kit | MORC3 elisa kit
Pigeon MORC Family CW-Type Zinc Finger Protein 3 (MORC3) ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016]
Uniprot Description
MORC3: Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233). {ECO:0000269|PubMed:11927593, ECO:0000269|PubMed:17332504, ECO:0000269|PubMed:20501696, ECO:0000269|PubMed:26202233}. Homodimer (PubMed:17332504). The sumoylated form interacts with PML (via SUMO-interacting motif) (PubMed:20501696, PubMed:17332504). Interacts with PT53 (PubMed:17332504). Interacts with influenza A virus PA and PB1 polymerase subunits during infection (PubMed:26202233). {ECO:0000269|PubMed:17332504, ECO:0000269|PubMed:20501696, ECO:0000269|PubMed:26202233}
Protein type: Cell cycle regulation; RNA-binding
Chromosomal Location of Human Ortholog: 21q22.13
Cellular Component: nuclear matrix; nucleoplasm; PML body
Molecular Function: RNA binding; zinc ion binding
Biological Process: cell aging; maintenance of protein localization in nucleus; negative regulation of fibroblast proliferation; peptidyl-serine phosphorylation; protein amino acid phosphorylation; protein stabilization; viral reproduction
Research Articles on MORC3
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Product Notes
The Pigeon MORC3 morc3 (Catalog #AAA9360626) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9360626 ELISA Kit recognizes Pigeon MORC3. It is sometimes possible for the material contained within the vial of "MORC Family CW-Type Zinc Finger Protein 3 (MORC3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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