Western Blot (WB)
(Western Blot analysis of AEBP2 in Mouse liver tissue using AEBP2 Rabbit pAb at dilution 1/220)
Rabbit anti-Human, Mouse AEBP2 Polyclonal Antibody | anti-AEBP2 antibody
AEBP2 Rabbit pAb
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
AEBP2; Polyclonal Antibody; AEBP2 Rabbit pAb; AE binding protein 2; anti-AEBP2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.3mg/ml (varies by lot)
Applicable Applications for anti-AEBP2 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
IHC-P: 1:25-1:100
IHC-P: 1:25-1:100
Immunogen
Fusion protein of human AEBP2
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Western Blot analysis of AEBP2 in Mouse liver tissue using AEBP2 Rabbit pAb at dilution 1/220)
Western Blot (WB)
(Western Blot analysis of AEBP2 in Mouse liver tissue using AEBP2 Rabbit pAb at dilution 1/220)
Immunohistochemistry (IHC)
(Immunohistochemistry of AEBP2 in paraffin-embedded Human breast cancer tissue using AEBP2 Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm)
Immunohistochemistry (IHC)
(Immunohistochemistry of AEBP2 in paraffin-embedded Human breast cancer tissue using AEBP2 Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm)
Related Product Information for anti-AEBP2 antibody
AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. The transcription of mammalian AEBP2 is driven by two alternative promoters and produces at least two isoforms of the protein. These isoforms show developmental stage-specific expression patterns: the adult-specific larger form (51 kDa) and the embryo-specific smaller form (32 kDa).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,981 Da
NCBI Official Full Name
zinc finger protein AEBP2 isoform b
NCBI Official Synonym Full Names
AE binding protein 2
NCBI Official Symbol
AEBP2
NCBI Protein Information
zinc finger protein AEBP2
UniProt Protein Name
Zinc finger protein AEBP2
Protein Family
UniProt Gene Name
AEBP2
UniProt Synonym Gene Names
AE-binding protein 2
UniProt Entry Name
AEBP2_HUMAN
Uniprot Description
AEBP2: DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. Belongs to the AEBP2/jing C2H2-type zinc-finger family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Transcription, coactivator/corepressor; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: ESC/E(Z) complex; nucleoplasm; nucleus
Biological Process: negative regulation of gene expression, epigenetic
Research Articles on AEBP2
Similar Products
Product Notes
The AEBP2 aebp2 (Catalog #AAA4758851) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AEBP2 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AEBP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:25-1:100. Researchers should empirically determine the suitability of the AEBP2 aebp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AEBP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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