Mouse protein phosphatase 1, regulatory (inhibitor) subunit 13 like ELISA Kit | PPP1R13L elisa kit

Mouse RelA-associated inhibitor, PPP1R13L ELISA Kit

Cat. Num. AAA9342162

• Gene Names: Ppp1r13l; wa3; IASPP; Nkip1; AV260376
• Reactivity: Mouse
• Synonyms: protein phosphatase 1; regulatory (inhibitor) subunit 13 like; Mouse RelA-associated inhibitor; PPP1R13L ELISA Kit; Mouse RelA-associated inhibitor (PPP1R13L) ELISA kit; IASPP; NKIP1; RAI; NFkB interacting protein 1; RelA-associated inhibitor; inhibitor of apoptosis stimulating protein of p53; regulatory subunit 13 like; PPP1R13L elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 58082069
• NCBI GeneID: 333654
• NCBI Accession #: NP_001010836.1
• NCBI GenBank Nucleotide #: NM_001010836.3
• UniProt Accession #: Q5I1X5
• Molecular Weight: 88,976 Da
• NCBI Official Full Name: relA-associated inhibitor
• NCBI Official Synonym Full Names: protein phosphatase 1, regulatory (inhibitor) subunit 13 like
• NCBI Official Symbol: Ppp1r13l
• NCBI Official Synonym Symbols: wa3; IASPP; Nkip1; AV260376
• NCBI Protein Information: relA-associated inhibitor; protein iASPP; PPP1R13B-like protein; inhibitor of ASPP protein; NFkB interacting protein 1; NFkB-interacting protein 1
• UniProt Protein Name: RelA-associated inhibitor
• Protein Family: RelA-associated inhibitor
• UniProt Gene Name: Ppp1r13l
• UniProt Synonym Gene Names: Nkip1; Protein iASPP
• UniProt Entry Name: IASPP_MOUSE

Uniprot Description

PPP1R13L: an oncoprotein that interacts with and inhibits NF-kappaB, Sp1 and p53. Plays a central role in regulation of apoptosis and transcription. May inhibit p53 by preventing its association with ASPP1 or ASPP2, thereby suppressing the subsequent activation of apoptosis. Required for neuronal survival after axonal injury. Two alternatively spliced isoforms have been described. Isoform 1 is preferrentially found in the cytoplasm; isoform 2 is nuclear.

Protein type: Phosphatase, regulatory subunit; Transcription, coactivator/corepressor; Apoptosis

Cellular Component: intercellular bridge; cytoplasm; nucleus; cell junction

Molecular Function: identical protein binding; protein binding; transcription factor binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis; multicellular organism growth; negative regulation of transcription from RNA polymerase II promoter; multicellular organismal homeostasis; positive regulation of cell differentiation; embryonic camera-type eye development; hair cycle; post-embryonic development; cardiac muscle contraction