Rat discs, large homolog 2 (Drosophila) ELISA Kit | DLG2 elisa kit
Rat Disks large homolog 2, DLG2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
membrane associated guanylate kinase localized at postsynaptic density (PSD); may function to maintain the structure of PSD by concentrating its components to the membrane area [RGD, Feb 2006]
Uniprot Description
PSD-93: Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses. Interacts through its PDZ domains with NETO1. Interacts with NOS1/nNOS through second PDZ domain. Interacts with KCNJ2/Kir2.1 (via C-terminus) through one of its PDZ domains. Interacts with FRMPD4 (via C-terminus). Interacts with LRFN1, LRFN2 and LRFN4. Interacts with FASLG. Belongs to the MAGUK family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Cellular Component: postsynaptic membrane; voltage-gated potassium channel complex; membrane; cell soma; basolateral plasma membrane; cytoplasm; postsynaptic density; dendrite; ionotropic glutamate receptor complex; cell junction
Molecular Function: protein C-terminus binding; ionotropic glutamate receptor binding; guanylate kinase activity; protein binding; protein heterodimerization activity; protein phosphatase binding; PDZ domain binding
Biological Process: establishment and/or maintenance of epithelial cell polarity; synaptic transmission; neuronal ion channel clustering; sensory perception of pain; receptor clustering; nucleotide phosphorylation
Research Articles on DLG2
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Product Notes
The Rat DLG2 dlg2 (Catalog #AAA9337673) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337673 ELISA Kit recognizes Rat DLG2. It is sometimes possible for the material contained within the vial of "discs, large homolog 2 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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