Human SCY1-like 1 (S. cerevisiae) ELISA Kit | SCYL1 elisa kit
Human N-terminal kinase-like protein, SCYL1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
SCYL1: Regulates COPI-mediated retrograde traffic. Has no detectable kinase activity in vitro. Belongs to the protein kinase superfamily. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Kinase, protein; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); Other group; SCY1 family
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: Golgi apparatus; cis-Golgi network; membrane; cytoplasm; ER-Golgi intermediate compartment; microtubule organizing center; COPI vesicle coat; nucleus
Molecular Function: DNA binding; protein-tyrosine kinase activity; ATP binding
Biological Process: peptidyl-tyrosine phosphorylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; retrograde vesicle-mediated transport, Golgi to ER
Research Articles on SCYL1
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Product Notes
The Human SCYL1 scyl1 (Catalog #AAA9337396) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337396 ELISA Kit recognizes Human SCYL1. It is sometimes possible for the material contained within the vial of "SCY1-like 1 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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