Human membrane-associated ring finger (C3HC4) 7 ELISA Kit | MARCH7 elisa kit

Human E3 ubiquitin-protein ligase MARCH7, MARCH7 ELISA Kit

Cat. Num. AAA9336745

• Gene Names: MARCH7; AXO; AXOT; RNF177; MARCH-VII
• Reactivity: Human
• Synonyms: membrane-associated ring finger (C3HC4) 7; Human E3 ubiquitin-protein ligase MARCH7; MARCH7 ELISA Kit; Human E3 ubiquitin-protein ligase MARCH7 (MARCH7) ELISA kit; AXO; AXOT; DKFZp586F1122; MARCH-VII; RNF177; OTTHUMP00000204988; axotrophin; membrane-associated RING-CH protein VII; MARCH7 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
• Assay Type: Sandwich (Quantitative)
• Detection Range: 0.625 ng/ml - 20 ng/ml.
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for MARCH7 elisa kit

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of MARCH7 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 544346245
• NCBI GeneID: 64844
• NCBI Accession #: NP_001269734.1
• NCBI GenBank Nucleotide #: NM_001282805.1
• UniProt Accession #: Q9H992; Q53GQ1; Q9BTR9; A8K9X1; B7Z7P5; D3DPB0
• Molecular Weight: 78,051 Da
• NCBI Official Full Name: E3 ubiquitin-protein ligase MARCH7 isoform a
• NCBI Official Synonym Full Names: membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase
• NCBI Official Symbol: MARCH7
• NCBI Official Synonym Symbols: AXO; AXOT; RNF177; MARCH-VII
• NCBI Protein Information: E3 ubiquitin-protein ligase MARCH7; axotrophin; RING finger protein 177; membrane-associated RING-CH protein VII; membrane-associated RING finger protein 7
• UniProt Protein Name: E3 ubiquitin-protein ligase MARCH7
• UniProt Gene Name: MARCH7
• UniProt Synonym Gene Names: AXOT; RNF177; MARCH-VII
• UniProt Entry Name: MARH7_HUMAN

NCBI Description

MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]

Uniprot Description

MARCH7: E3 ubiquitin-protein ligase which may specifically enhance the E2 activity of HIP2. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Protein type: Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system; EC 6.3.2.-; Ligase

Chromosomal Location of Human Ortholog: 2q24.2

Molecular Function: zinc ion binding; ligase activity

Biological Process: protein ubiquitination