Human WAP four-disulfide core domain 1 ELISA Kit | WFDC1 elisa kit

Human WAP four-disulfide core domain protein 1, WFDC1 ELISA Kit

Cat. Num. AAA9334978

• Gene Names: WFDC1; PS20
• Reactivity: Human
• Synonyms: WAP four-disulfide core domain 1; Human WAP four-disulfide core domain protein 1; WFDC1 ELISA Kit; Human WAP four-disulfide core domain protein 1 (WFDC1) ELISA kit; PS20; WAP four-disulfide core domain 1 homolog; prostate stromal protein ps20; WFDC1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples.
• Assay Type: Sandwich
• Detection Range: 31.2 pg/ml - 1000 pg/ml.
• Sensitivity: 5.0 pg/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%.
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for WFDC1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of WFDC1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 541862107
• NCBI GeneID: 58189
• NCBI Accession #: NP_001269395.1
• NCBI GenBank Nucleotide #: NM_001282466.1
• UniProt Accession #: Q9HC57; Q8NC27; Q9HAU1; D3DUL7
• Molecular Weight: 23,977 Da
• NCBI Official Full Name: WAP four-disulfide core domain protein 1 isoform 1
• NCBI Official Synonym Full Names: WAP four-disulfide core domain 1
• NCBI Official Symbol: WFDC1
• NCBI Official Synonym Symbols: PS20
• NCBI Protein Information: WAP four-disulfide core domain protein 1; ps20 growth inhibitor; prostate stromal protein ps20; WAP four-disulfide core domain 1 homolog
• UniProt Protein Name: WAP four-disulfide core domain protein 1
• Protein Family: WAP four-disulfide core domain protein
• UniProt Gene Name: WFDC1
• UniProt Synonym Gene Names: PS20
• UniProt Entry Name: WFDC1_HUMAN

NCBI Description

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Uniprot Description

WFDC1: Has growth inhibitory activity.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: extracellular space

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: response to drug; negative regulation of cell growth; response to estradiol stimulus; negative regulation of epithelial cell proliferation