Human vacuolar protein sorting 11 homolog (S. cerevisiae) ELISA Kit | VPS11 elisa kit

Human Vacuolar protein sorting-associated protein 11 homolog, VPS11 ELISA Kit

Cat. Num. AAA9333928

• Gene Names: VPS11; END1; PEP5; RNF108; hVPS11
• Reactivity: Human
• Synonyms: vacuolar protein sorting 11 homolog (S. cerevisiae); Human Vacuolar protein sorting-associated protein 11 homolog; VPS11 ELISA Kit; Human Vacuolar protein sorting-associated protein 11 homolog (VPS11) ELISA kit; END1; PEP5; RNF108; hVPS11; vacuolar protein sorting 11; vacuolar protein sorting protein 11; VPS11 elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 589058161
• NCBI GeneID: 55823
• NCBI Accession #: NP_001277114.1
• NCBI GenBank Nucleotide #: NM_001290185.1
• UniProt Accession #: Q9H270; Q8WY89; Q96EP8; Q9H6D9; Q9HCS6
• Molecular Weight: 107,837 Da
• NCBI Official Full Name: vacuolar protein sorting-associated protein 11 homolog isoform 2
• NCBI Official Synonym Full Names: vacuolar protein sorting 11 homolog (S. cerevisiae)
• NCBI Official Symbol: VPS11
• NCBI Official Synonym Symbols: END1; PEP5; RNF108; hVPS11
• NCBI Protein Information: vacuolar protein sorting-associated protein 11 homolog; RING finger protein 108
• UniProt Protein Name: Vacuolar protein sorting-associated protein 11 homolog
• Protein Family: Vacuolar protein sorting-associated protein
• UniProt Gene Name: VPS11
• UniProt Synonym Gene Names: RNF108; PP3476; hVPS11
• UniProt Entry Name: VPS11_HUMAN

NCBI Description

Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Uniprot Description

VPS11: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Belongs to the VPS11 family.

Protein type: Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: endocytic vesicle; lysosome; late endosome membrane; lysosomal membrane; late endosome; endosome

Molecular Function: protein binding; syntaxin binding; zinc ion binding; nucleotide binding

Biological Process: vesicle-mediated transport; intracellular protein transport