Mouse nuclear receptor subfamily 2, group E, member 1 ELISA Kit | NR2E1 elisa kit
Mouse Nuclear receptor subfamily 2 group E member 1, NR2E1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
NR2E1: Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half- site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acic receptor (RAR) regulation in retinal cells. Belongs to the nuclear hormone receptor family. NR2 subfamily.
Protein type: Nuclear receptor; DNA-binding
Cellular Component: nucleus
Molecular Function: protein binding; enzyme binding; DNA binding; zinc ion binding; sequence-specific DNA binding; metal ion binding; histone deacetylase binding; steroid hormone receptor activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; extracellular matrix organization and biogenesis; behavioral fear response; somatic stem cell maintenance; regulation of dendrite morphogenesis; multicellular organismal development; regulation of timing of neuron differentiation; amygdala development; negative regulation of transcription from RNA polymerase II promoter; cerebral cortex neuron differentiation; visual perception; regulation of transcription, DNA-dependent; regulation of cellular component organization and biogenesis; positive regulation of cell proliferation; layer formation in the cerebral cortex; cell fate commitment; camera-type eye development; dentate gyrus development; generation of neurons in the forebrain; transcription, DNA-dependent; olfactory bulb development; positive regulation of cell cycle; social behavior; glial cell migration; positive regulation of angiogenesis; negative regulation of neuron differentiation; anterior commissure morphogenesis; retina development in camera-type eye; negative regulation of astrocyte differentiation; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex development; brain development; negative regulation of apoptosis
Research Articles on NR2E1
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Product Notes
The Mouse NR2E1 nr2e1 (Catalog #AAA9333229) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9333229 ELISA Kit recognizes Mouse NR2E1. It is sometimes possible for the material contained within the vial of "nuclear receptor subfamily 2, group E, member 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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